Author

N. T. Pham

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Microbiology· 2 Bioengineering· 1 Biophysics· 1 Cell Biology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:drug response / drug discovery· 4 Organism:human· 4 Research Focus:cell type annotation· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:database / resource· 1 Approach:deep learning· 1

Frequent Co-Authors

M. Auer· 5 shared J. Wildenhain· 3 shared A. Rizzotto· 2 shared E. C. Schirmer· 2 shared S. Tollis· 2 shared A. A. Jeyaprakash· 1 shared A. M. Lipzen· 1 shared A. N. Bui· 1 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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5 shared papersCancer Biology

M. Auer

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Estradiol propionate reduction of nuclear size in prostate cancer lines lacking DHRS7suggests DHRS7 absence as a biomarker for the effectiveness of estrogen therapy

A. Rizzotto, S. Tollis, N. T. Pham, Y. Zheng, M. A. Abad, J. Wildenhain, A. A. Jeyaprakash, M. Auer, M. D. Tyers, E. C. Schirmer

The paper shows that DHRS7 loss increases nuclear size in prostate cancer cells and that estradiol propionate reduces nuclear size in DHRS7-lacking cells, suggesting DHRS7 as a biomarker for estrogen therapy effectiveness.

bioRxiv · Sep 18, 2023 · PreprintCancer Biology

Long-term epidemiology and evolution of swine influenza viruses in Vietnam

J. Cheung, A. N. Bui, S. Younas, K. M. Edwards, H. Q. Nguyen, N. T. Pham, V. N. Bui, M. Peiris, V. Dhanasekaran

The paper tracks the long-term epidemiology and evolution of swine influenza viruses in Vietnam, identifying gene pool enrichment and reassortment events.

bioRxiv · Feb 8, 2023 · PreprintMicrobiology

Nanoscaled discovery of a shunt rifamycin from Salinispora arenicola using a three-colour GFP-tagged Staphylococcus aureus macrophage infection assay.

N. T. Pham, J. Alves, F. A. Sargison, R. Cullum, J. Wildenhain, W. Fenical, M. S. Butler, D. Mead, B. M. Duggan, J. R. Fitzgerald, J. J. La Clair, M. Auer

The paper uses a GFP-tagged S. aureus macrophage infection assay to discover a novel rifamycin analogue with macrophage intracellular activity.

bioRxiv · Dec 4, 2022 · PreprintCell Biology

Nanoparticles targeted to fibroblast activation protein outperform PSMA for MRI delineation of primary prostate tumours

N. Dmochowska, V. Milanova, R. Mukkamala, K. K. Chow, N. T. Pham, M. Srinivasarao, L. M. Ebert, T. Stait-Gardner, H. Le, A. Shetty, M. Nelson, P. S. Low, B. Thierry

This study compares FAP-targeted MRI with PSMA-targeted MRI for delineating prostate tumors in mice, finding FAP provides better contrast enhancement.

bioRxiv · Jun 10, 2022 · PreprintBioengineering

PyBindingCurve, simulation and curve fitting to complex binding systems at equilibrium.

S. Shave, Y.-K. Chen, N. T. Pham, M. Auer

PyBindingCurve simulates and fits equilibrium binding systems, revealing that homodimers are more easily inhibited and depleted than heterodimers under specific conditions.

bioRxiv · Nov 6, 2020Biophysics

Chemical-Genetic Interrogation of Nuclear Size Control Reveals Cancer-Specific Effects on Cell Migration and Invasion

A. Rizzotto, S. Tollis, N. T. Pham, J. Wildenhain, N. Zuleger, J. T. Keys, D. Batrakou, J. Culley, S. Zheng, J. Lammerding, N. O. Carragher, V. Brunton, M. Auer, M. Tyers, E. C. Schirmer

The paper identifies compounds that reverse nuclear size changes in cancer cell lines and finds they inhibit cell migration and invasion.

bioRxiv · Jan 10, 2020 · PreprintCancer Biology

Asparagine deprivation causes a reversible inhibition of Human Cytomegalovirus acute virus replication

C.-H. Lee, S. Griffiths, P. Digard, N. T. Pham, M. Auer, J. Haas, F. Grey

This study identifies asparagine as a critical factor for HCMV replication through a large-scale siRNA screen, showing that its depletion inhibits virus replication but allows recovery with exogenous asparagine.

mBio · Oct 29, 2019Peer-reviewedMicrobiology

The Sequence of 1504 Mutants in the Model Rice Variety Kitaake Facilitates Rapid Functional Genomic Studies

G. Li, R. Jain, M. Chern, N. T. Pham, J. A. Martin, T. Wei, W. S. Schackwitz, A. M. Lipzen, P. Q. Duong, K. C. Jones, L. Jiang, D. Ruan, D. Bauer, Y. Peng, K. W. Barry, , P. C. Ronald

The paper sequenced 1,504 mutant lines in the rice variety Kitaake and established a database to enable rapid functional genomic studies.

bioRxiv · Feb 24, 2017Plant Biology