Author

J. Wildenhain

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:fluorescence / live-cell microscopy· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

M. Auer· 3 shared N. T. Pham· 3 shared A. Rizzotto· 2 shared E. C. Schirmer· 2 shared S. Tollis· 2 shared A. A. Jeyaprakash· 1 shared B. M. Duggan· 1 shared D. Batrakou· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersCancer Biology

M. Auer

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Estradiol propionate reduction of nuclear size in prostate cancer lines lacking DHRS7suggests DHRS7 absence as a biomarker for the effectiveness of estrogen therapy

A. Rizzotto, S. Tollis, N. T. Pham, Y. Zheng, M. A. Abad, J. Wildenhain, A. A. Jeyaprakash, M. Auer, M. D. Tyers, E. C. Schirmer

The paper shows that DHRS7 loss increases nuclear size in prostate cancer cells and that estradiol propionate reduces nuclear size in DHRS7-lacking cells, suggesting DHRS7 as a biomarker for estrogen therapy effectiveness.

bioRxiv · Sep 18, 2023 · PreprintCancer Biology

Nanoscaled discovery of a shunt rifamycin from Salinispora arenicola using a three-colour GFP-tagged Staphylococcus aureus macrophage infection assay.

N. T. Pham, J. Alves, F. A. Sargison, R. Cullum, J. Wildenhain, W. Fenical, M. S. Butler, D. Mead, B. M. Duggan, J. R. Fitzgerald, J. J. La Clair, M. Auer

The paper uses a GFP-tagged S. aureus macrophage infection assay to discover a novel rifamycin analogue with macrophage intracellular activity.

bioRxiv · Dec 4, 2022 · PreprintCell Biology

Chemical-Genetic Interrogation of Nuclear Size Control Reveals Cancer-Specific Effects on Cell Migration and Invasion

A. Rizzotto, S. Tollis, N. T. Pham, J. Wildenhain, N. Zuleger, J. T. Keys, D. Batrakou, J. Culley, S. Zheng, J. Lammerding, N. O. Carragher, V. Brunton, M. Auer, M. Tyers, E. C. Schirmer

The paper identifies compounds that reverse nuclear size changes in cancer cell lines and finds they inhibit cell migration and invasion.

bioRxiv · Jan 10, 2020 · PreprintCancer Biology