Author

D. Goulet

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. A. Lane· 1 shared A. B. Miller· 1 shared A. Langenbucher· 1 shared A. Legros· 1 shared A. Ramos· 1 shared A. Regev· 1 shared A. Thomas· 1 shared C. Bray· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperCancer Biology

A. A. Lane

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Author profile →

3 papers

Recent·Most cited

Leukemia circulation kinetics revealed through blood exchange method

A. B. Miller, A. Langenbucher, F. H. Rodriguez, L. Lin, C. Bray, S. Duquette, Y. Zhang, D. Goulet, A. A. Lane, D. M. Weinstock, M. T. Hemann, S. R. Manalis

This study uses a blood exchange method in mouse leukemia models to show that leukemia cells circulate longer than solid tumor cells and that microenvironmental factors like E-selectin influence their clearance.

bioRxiv · Sep 3, 2023Cancer Biology

Leukemia-intrinsic determinants of CAR-T response revealed by iterative in vivo genome-wide CRISPR screening.

A. Ramos, C. E. Koch, Y. Liu, R. D. Hellinger, T. Kyung, K. L. Abbott, J. Froese, D. Goulet, K. S. Gordon, R. C. Larson, J. G. Doench, A. Regev, M. G. Vander Heiden, M. V. Maus, M. E. Birnbaum, M. Hemann

This study identifies leukemia-intrinsic resistance mechanisms to CAR-T therapy through in vivo CRISPR screening in a murine B-ALL model, revealing IFNγ/JAK/STAT and antigen processing pathways as key mediators.

bioRxiv · Feb 15, 2022 · PreprintCancer Biology

Magnetophospenes in humans exposed to ELF MF up to 50 mT, a threshold study

A. Legros, J. Modolo, M. Corbacio, D. Goulet, M. Plante, M. Souques, F. Deschamps, G. Ostiguy, J. Lambrozo, A. Thomas

This study determines the magnetic field thresholds triggering magnetophosphenes in humans at specific frequencies, finding frequency-dependent thresholds and the need to report values as dB/dt.

bioRxiv · Oct 10, 2018 · PreprintBiophysics