Author

D. L. Plubell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3

Signature Assays, Organisms & Methods

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Assay:proteomics· 3 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

C. C. Wu· 3 shared M. J. MacCoss· 3 shared A. N. Hoofnagle· 2 shared E. Huang· 2 shared G. E. Merrihew· 2 shared J. Park· 2 shared K. A. Tsantilas· 2 shared M. Riffle· 2 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersBiochemistry

C. C. Wu

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Author profile →

3 papers

Recent·Most cited

A framework for quality control in quantitative proteomics

K. A. Tsantilas, G. E. Merrihew, J. E. Robbins, R. S. Johnson, J. Park, D. L. Plubell, J. D. Canterbury, E. Huang, M. Riffle, V. Sharma, B. X. MacLean, J. Eckels, C. C. Wu, M. S. Bereman, S. E. Spencer, , M. J. MacCoss

The paper introduces a framework for quality control in quantitative proteomics, combining internal and external QC measures with tools for data analysis and deposition.

bioRxiv · Apr 12, 2024Biochemistry

Mag-Net: Rapid enrichment of membrane-bound particles enables high coverage quantitative analysis of the plasma proteome

C. C. Wu, K. A. Tsantilas, J. Park, D. L. Plubell, J. A. Sanders, P. Naicker, I. Govender, S. Buthelezi, S. Stoychev, J. Jordaan, G. E. Merrihew, E. Huang, E. D. Parker, M. Riffle, A. N. Hoofnagle, , M. J. MacCoss

Mag-Net enriches membrane-bound particles from plasma to identify disease-specific proteins, discovering 204 proteins differentiating Alzheimer's disease dementia from controls.

bioRxiv · Jun 10, 2023 · PreprintBiochemistry

Can we put Humpty Dumpty back together again? What does protein quantification mean in bottom-up proteomics?

D. L. Plubell, L. Käll, B.-J. Webb-Robertson, L. Bramer, A. Ives, N. L. Kelleher, L. M. Smith, T. J. Montine, C. C. Wu, M. J. MacCoss

The paper questions the assumption that all peptides from a protein coding gene represent the same protein quantity in bottom-up proteomics, highlighting the need for better methods to account for proteomic complexity.

bioRxiv · Jan 25, 2021 · PreprintBiochemistry