Author

G. E. Merrihew

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Cell Biology· 2

Signature Assays, Organisms & Methods

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Assay:proteomics· 5 Approach:experimental assay· 4 Research Focus:benchmarking· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1

Frequent Co-Authors

M. J. MacCoss· 5 shared E. Huang· 3 shared A. N. Hoofnagle· 2 shared C. C. Wu· 2 shared D. L. Plubell· 2 shared J. E. Robbins· 2 shared J. Park· 2 shared K. A. Tsantilas· 2 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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5 shared papersBiochemistry

M. J. MacCoss

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Author profile →

5 papers

Recent·Most cited

A framework for quality control in quantitative proteomics

K. A. Tsantilas, G. E. Merrihew, J. E. Robbins, R. S. Johnson, J. Park, D. L. Plubell, J. D. Canterbury, E. Huang, M. Riffle, V. Sharma, B. X. MacLean, J. Eckels, C. C. Wu, M. S. Bereman, S. E. Spencer, , M. J. MacCoss

The paper introduces a framework for quality control in quantitative proteomics, combining internal and external QC measures with tools for data analysis and deposition.

bioRxiv · Apr 12, 2024Biochemistry

Comparing peptide identifications by FAIMS versus quadrupole gas-phase fractionation

D. A. Faivre, C. D. McGann, G. E. Merrihew, D. K. Schweppe, M. J. MacCoss

This study compares FAIMS and quadrupole gas-phase fractionation in peptide identification, finding that FAIMS improves results mainly by reducing co-isolation of precursor ions and chimeric spectra.

bioRxiv · Sep 1, 2023 · PreprintBiochemistry

Mag-Net: Rapid enrichment of membrane-bound particles enables high coverage quantitative analysis of the plasma proteome

C. C. Wu, K. A. Tsantilas, J. Park, D. L. Plubell, J. A. Sanders, P. Naicker, I. Govender, S. Buthelezi, S. Stoychev, J. Jordaan, G. E. Merrihew, E. Huang, E. D. Parker, M. Riffle, A. N. Hoofnagle, , M. J. MacCoss

Mag-Net enriches membrane-bound particles from plasma to identify disease-specific proteins, discovering 204 proteins differentiating Alzheimer's disease dementia from controls.

bioRxiv · Jun 10, 2023 · PreprintBiochemistry

Elamipretide (SS-31) Treatment Attenuates Age-Associated Post-Translational Modifications of Heart Proteins

J. A. Whitson, M. Martin-Perez, T. Zhang, M. J. Gaffrey, G. E. Merrihew, E. Huang, C. C. White, T. J. Kavanagh, W.-J. Qian, M. D. Campbell, M. J. MacCoss, D. J. Marcinek, J. Villen, P. S. Rabinovitch

This study investigates how elamipretide affects age-related post-translational modifications in mouse heart proteins, finding that it reverses oxidative changes but not phosphorylation changes.

bioRxiv · Aug 6, 2021Cell Biology

Isolation and characterization of extracellular vesicles from Caenorhabditis elegans for multi-omic analysis.

J. C. Russell, G. E. Merrihew, J. E. Robbins, N. Postupna, T.-K. Kim, A. Golubeva, A. Noori, K. Wang, C. D. Keene, M. J. MacCoss, M. Kaeberlein

This paper isolates and characterizes extracellular vesicles from C. elegans, showing they share key properties with mammalian EVs and enabling multi-omic analysis.

bioRxiv · Nov 25, 2018Cell Biology