Author

D. Little

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Ecology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

B. Kim· 1 shared C. Kim· 1 shared C.-L. Wu· 1 shared D. Corcoran· 1 shared F. Guilak· 1 shared G. Jackson· 1 shared G. Malloch· 1 shared G. Zou· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperCell Biology

B. Kim

Mutual co-authors in cluster

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3 papers

Recent·Most cited

PCLAF-DREAM Drives Alveolar Cell Plasticity for Lung Regeneration

B. Kim, Y. Huang, K.-P. Ko, S. Zhang, G. Zou, J. Zhang, M. Kim, D. Little, L. V. Ellis, M. Paschini, S. Jun, K.-S. Park, J. Chen, C. Kim, J.-I. Park

This study identifies PCLAF-DREAM's role in alveolar cell plasticity during lung regeneration and shows a drug candidate can pharmacologically target this process to prevent fibrosis.

bioRxiv · Oct 11, 2022Cell Biology

Aging and Obesity Prime the Methylome and Transcriptome of Adipose Stem Cells for Disease and Dysfunction

S. Xie, S. Choudhari, C.-L. Wu, K. Abramson, D. Corcoran, S. G. Gregory, J. M. Thimmapuram, F. Guilak, D. Little

This study identifies epigenetic and transcriptomic changes in adipose stem cells due to aging and obesity, revealing synergistic effects and potential disease-related regulators.

bioRxiv · Sep 26, 2022Cell Biology

Grain aphids (Sitobion avenae) with knockdown resistance (kdr) to insecticide exhibit fitness trade-offs, including increased vulnerability to the natural enemy Aphidius ervi.

G. Jackson, G. Malloch, L. McNamara, D. Little

This study examines fitness costs of insecticide resistance in grain aphids and finds increased vulnerability to a parasitoid, suggesting potential for biological control.

bioRxiv · Mar 4, 2020Ecology