Author

S. G. Gregory

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 3 Cell Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:spatial transcriptomics· 2 Approach:statistical model· 2

Frequent Co-Authors

D. G. Kirsch· 2 shared D. M. Ashley· 2 shared E. Hocke· 2 shared J. A. Regal· 2 shared K. Abramson· 2 shared M. E. Guerra Garcia· 2 shared V. Jain· 2 shared Z. J. Reitman· 2 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

D. G. Kirsch

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

UBE2N is essential for maintenance of skin homeostasis and suppression of inflammation

M. J. Lee, M. Ben Hammouda, W. Miao, A. Okafor, Y. Jin, H. Sun, V. Jain, V. Markovtsov, Y. Diao, S. G. Gregory, J. Y. Zhang

This study shows that UBE2N is crucial for skin homeostasis and inflammation suppression, with its loss causing inflammatory skin defects and identifying IRAK1/4 as a therapeutic target.

bioRxiv · Dec 1, 2023Pathology

Ataxia-telangiectasia mutated (Atm) disruption sensitizes spatially-directed H3.3K27M/TP53 diffuse midline gliomas to radiation therapy

A. Mangoli, S. Wu, H. Q. Liu, M. Aksu, V. J. Jain, B. E. Foreman, J. A. Regal, L. B. Weidenhammer, C. E. Stewart, M. E. Guerra Garcia, E. Hocke, K. Abramson, N. T. Williams, L. Luo, K. Deland, , Z. J. Reitman

This study shows that disrupting ATM enhances radiation therapy efficacy in p53-mutant DMGs but not p53-wildtype DMGs using mouse models.

bioRxiv · Oct 18, 2023Cancer Biology

Ganglioglioma deep transcriptomics reveals primitive neuroectoderm neural precursor-like population

J. A. Regal, M. E. Guerra Garcia, V. Jain, V. Chandramohan, D. M. Ashley, S. G. Gregory, E. M. Thompson, G. Y. Lopez, Z. J. Reitman

This study uses deep transcriptomic analyses to identify a CD34+ neuroectoderm-like population in gangliogliomas, revealing its role as a precursor cell controlling tumor heterogeneity and immune interactions.

Acta Neuropathologica Communications · Mar 25, 2023Peer-reviewedCancer Biology

Aging and Obesity Prime the Methylome and Transcriptome of Adipose Stem Cells for Disease and Dysfunction

S. Xie, S. Choudhari, C.-L. Wu, K. Abramson, D. Corcoran, S. G. Gregory, J. M. Thimmapuram, F. Guilak, D. Little

This study identifies epigenetic and transcriptomic changes in adipose stem cells due to aging and obesity, revealing synergistic effects and potential disease-related regulators.

bioRxiv · Sep 26, 2022Cell Biology

The Na+/K+ ATPase Regulates Glycolysis and Modifies Immune metabolism in Tumors

S. M. Sanderson, Z. Xiao, A. J. Wisdom, S. Bose, M. V. Liberti, M. A. Reid, E. Hocke, S. G. Gregory, D. G. Kirsch, J. W. Locasale

This study shows that Na+/K+ ATPase inhibition via digoxin disrupts glycolysis in tumor and healthy cells, alters immune metabolism, and changes tumor microenvironment composition.

bioRxiv · Mar 31, 2020 · PreprintCancer Biology