Author

D. Masopust

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:mouse· 5 Research Focus:cell type annotation· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1

Frequent Co-Authors

S. Wijeyesinghe· 3 shared E. Weyu· 2 shared P. C. Rosato· 2 shared S. O'Flanagan· 2 shared V. Vezys· 2 shared A. G. J. Skorput· 1 shared A. G. Soerens· 1 shared A. L. Sarver· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersImmunology

S. Wijeyesinghe

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Collaboration between IL-7 and IL-15 enables adaptation of tissue-resident and circulating memory CD8+ T cells

N. N. Jarjour, T. S. Dalzell, N. J. Maurice, K. M. Wanhainen, C. Peng, T. A. DePauw, K. E. Block, W. J. Valente, K. M. Ashby, D. Masopust, S. C. Jameson

This study shows that IL-7 and IL-15 collaborate to support memory CD8+ T cells, with IL-7R required for self-renewal and IL-15 imposing dependence on IL-7R.

bioRxiv · May 31, 2024Immunology

Differential migration mechanics and immune responses of glioblastoma subtypes

G. A. Shamsan, C. J. Liu, B. C. Braman, R. Li, S. K. Rathe, A. L. Sarver, N. Ghaderi, M. M. McMahon, R. L. Klank, B. R. Tschida, S. J. McFarren, P. C. Rosato, D. Masopust, J. N. Sarkaria, H. B. Clark, , D. J. Odde

This study shows mesenchymal glioblastoma cells migrate faster and generate more traction force than proneural cells, but their immunologically hot environment improves survival despite aggressive growth.

bioRxiv · Jun 26, 2022 · PreprintCancer Biology

Route of self-amplifying mRNA vaccination modulates the establishment of pulmonary resident memory CD8 and CD4 T cells

M. Kunzli, S. O'Flanagan, M. LaRue, P. Talukder, T. Dileepan, A. Soerens, C. Quarnstrom, S. Wijeyesinghe, Y. Ye, J. McPartlan, J. Mitchell, C. Mandl, R. Vile, M. Jenkins, R. Ahmed, , D. Masopust

This study investigates how different routes of self-amplifying mRNA vaccination affect the establishment of pulmonary resident memory T cells in mice.

bioRxiv · Jun 2, 2022Immunology

Therapeutic activation of virus-specific resident memory T cells within the glioblastoma microenvironment

J. Ning, N. Gavil, S. Wu, S. Wijeyesinghe, E. Weyu, J. Ma, M. Li, F.-N. Grigore, S. Dhawan, A. G. J. Skorput, S. C. Musial, C. C. Chen, D. Masopust, P. C. Rosato

This study shows that virus-specific memory T cells reside in glioblastoma and can be reactivated to improve survival in a mouse model.

bioRxiv · Sep 6, 2021 · PreprintImmunology

Nucleocapsid vaccine elicits spike-independent SARS-CoV-2 protective immunity

W. E. Matchett, V. Joag, J. M. Stolley, F. K. Shephard, C. F. Quarnstrom, C. K. Mickelson, S. Wijeyesinghe, A. G. Soerens, S. Becker, J. M. Thiede, E. Weyu, S. O'Flanagan, J. Walter, M. N. Vu, V. D. Menachery, , D. Masopust

This study shows that a nucleocapsid protein vaccine provides protective immunity against SARS-CoV-2, independent of spike protein targeting, in animal models.

bioRxiv · Apr 26, 2021Immunology