Author

J. M. Thiede

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 3 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Assay:flow cytometry· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

R. A. Langlois· 3 shared T. D. Bold· 3 shared V. D. Menachery· 3 shared W. E. Matchett· 3 shared A. D. Baughn· 2 shared M. K. Jenkins· 2 shared Y. Minato· 2 shared A. G. Soerens· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersImmunology

R. A. Langlois

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Nucleocapsid vaccine elicits spike-independent SARS-CoV-2 protective immunity

W. E. Matchett, V. Joag, J. M. Stolley, F. K. Shephard, C. F. Quarnstrom, C. K. Mickelson, S. Wijeyesinghe, A. G. Soerens, S. Becker, J. M. Thiede, E. Weyu, S. O'Flanagan, J. Walter, M. N. Vu, V. D. Menachery, , D. Masopust

This study shows that a nucleocapsid protein vaccine provides protective immunity against SARS-CoV-2, independent of spike protein targeting, in animal models.

bioRxiv · Apr 26, 2021Immunology

Pyrazinamide action is driven by the cell envelope stress response in Mycobacterium tuberculosis

J. M. Thiede, N. Dillon, M. D. Howe, S. J. Modlin, R. Aflakpui, S. Hoffner, F. Valafar, Y. Minato, A. D. Baughn

This study identifies that the cell envelope stress response drives pyrazinamide susceptibility in Mycobacterium tuberculosis, independent of pH, and shows that peptidoglycan synthesis inhibitors enhance its action.

bioRxiv · Feb 17, 2021 · PreprintMicrobiology

Single cell resolution of SARS-CoV-2 tropism, antiviral responses, and susceptibility to therapies in primary human airway epithelium

J. K. Fiege, J. M. Thiede, H. Nanda, W. E. Matchett, P. J. Moore, N. R. Montanari, B. K. Thielen, J. Daniel, E. Stanley, R. C. Hunter, V. D. Menachery, S. S. Shen, T. D. Bold, R. A. Langlois

This study investigates SARS-CoV-2 tropism, antiviral responses, and therapy effectiveness in human airway epithelium using single-cell RNA-sequencing and flow cytometry.

bioRxiv · Oct 19, 2020Microbiology

SARS-CoV-2 neutralization and serology testing of COVID-19 convalescent plasma from donors with non-severe disease

T. J. Gniadek, J. M. Thiede, W. E. Matchett, A. R. Gress, K. A. Pape, M. K. Jenkins, V. D. Menachery, R. A. Langlois, T. D. Bold

The paper assesses SARS-CoV-2 neutralization and serology in convalescent plasma from non-severe COVID-19 donors, finding correlations between binding activity and neutralization.

bioRxiv · Aug 7, 2020Immunology

Genome-wide assessment of Mycobacterium tuberculosis conditionally essential metabolic pathways

Y. Minato, D. M. Gohl, J. M. Thiede, J. M. Chacon, W. R. Harcombe, F. Maruyama, A. D. Baughn

This study identifies conditionally essential metabolic pathways in Mycobacterium tuberculosis using Tn-seq and in silico models, revealing gaps in current knowledge of its metabolic capabilities.

bioRxiv · May 14, 2019 · PreprintMicrobiology