Author

D. Takahashi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Immunology· 2 Plant Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell signaling & trafficking· 3 Assay:proteomics· 3 Organism:bacteria (other)· 2 Research Focus:cell type annotation· 2 Approach:statistical model· 2 Organism:Arabidopsis· 1 Approach:benchmark study· 1

Frequent Co-Authors

I. Fujiwara· 2 shared M. Miyata· 2 shared A. Bacic· 1 shared A. J. Nagano· 1 shared A. Narita· 1 shared A. Ojida· 1 shared A. Sampathkumar· 1 shared A. Sato· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 5 mutual co-author links

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2 shared papersBiophysics

I. Fujiwara

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Cell wall pectic β-1,4-galactan contributes to increased plant freezing tolerance induced by cold acclimation

D. Takahashi, K. Soga, K. Sasaki, T. Kikuchi, T. Kutsuno, Y. Nishiyama, K. L. Johnson, A. Sampathkumar, A. Bacic, T. Kotake

This study shows that cold acclimation increases β-1,4-galactan in plant cell walls, improving freezing tolerance by altering cell wall mechanical properties.

bioRxiv · May 31, 2023 · PreprintPlant Biology

Assembly properties of Spiroplasma MreB involved in swimming motility

D. Takahashi, M. Miyata, I. Fujiwara

This study examines the assembly properties of SpeMreB5, a component of the Spiroplasma swimming ribbon, revealing conditions and interactions that influence its formation and aggregation.

bioRxiv · Jan 26, 2023 · PreprintBiophysics

Discovery of Chlorofluoroacetamide-Based Covalent Inhibitors for SARS-CoV-2 3CL Protease

Y. Hirose, N. Shindo, M. Mori, S. Onitsuka, H. Isogai, R. Hamada, T. Hiramoto, J. Ochi, D. Takahashi, T. Ueda, J. M. M. Caaveiro, Y. Yoshida, S. Ohdo, N. Matsunaga, S. Toba, , A. Ojida

The paper identifies a new class of covalent inhibitors for SARS-CoV-2 3CL protease with chlorofluoroacetamide warhead, showing potent antiviral activity comparable to nirmatrelvir.

bioRxiv · Jun 5, 2022Biochemistry

Maternal Western-Style Diet Impairs Bone Marrow Development and Drives a Hyperinflammatory Phenotype in Hematopoietic Stem and Progenitor Cells in Fetal Rhesus Macaques

S. Sureshchandra, C. N. Chan, J. J. Robino, L. K. Parmelee, M. J. Nash, S. R. Wesolowski, E. M. Pietras, J. E. Friedman, D. Takahashi, W. Shen, J. D. Hennebold, D. Goldman, W. Packwood, J. R. Lindner, C. T. Roberts, , O. Varlamov

This study shows that a maternal Western-style diet impairs fetal bone marrow development and causes hyperinflammation and B-cell dysfunction in fetal hematopoietic stem and progenitor cells in rhesus macaques.

bioRxiv · Apr 26, 2021 · PreprintImmunology

ATP dependent polymerization dynamics of bacterial actin proteins involved in Spiroplasma swimming

D. Takahashi, I. Fujiwara, Y. Sasajima, A. Narita, K. Imada, M. Miyata

The paper investigates the structure, ATPase activity, and polymerization dynamics of two MreB homologs in Spiroplasma eriocheiris, finding differences in their polymerization behavior and ATP hydrolysis mechanisms.

bioRxiv · Apr 7, 2021Biophysics

Epithelial HVEM promotes basement membrane synthesis and intraepithelial T cell survival and migration

D. Takahashi, Q. Wang, G.-Y. Seo, J.-W. Shui, Z. Mikulski, P. Marcovecchio, M. Takahashi, C. D. Surh, H. Cheroutre, M. Kronenberg

This study shows that epithelial HVEM supports basement membrane synthesis and IET survival and migration in the intestine.

bioRxiv · Sep 30, 2020 · PreprintImmunology

Geographic and subsequent biotic isolations led to a diversity anomaly of Heterotropa (Aristolochiaceae) in insular versus continental regions of the Sino-Japanese Floristic Region

D. Takahashi, Y. Feng, S. Sakaguchi, Y. Isagi, Y.-X. Qiu, P. Li, R.-S. Lu, C.-T. Lu, S.-W. Chung, Y.-S. Lin, Y.-C. Chen, A. J. Nagano, L. Kawaguchi, H. Setoguchi

This study investigates the diversity anomaly of Heterotropa in insular versus continental regions by analyzing phylogenetic relationships and floral trait evolution.

bioRxiv · Apr 25, 2020Plant Biology