Author

D. van Sinderen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:mouse· 3 Assay:metabolomics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Organism:chicken / avian· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

L. J. Hall· 3 shared A. Treveil· 2 shared M. J. Dalby· 2 shared R. Kiu· 2 shared S. Caim· 2 shared T. Korcsmaros· 2 shared A. L. Shiver· 1 shared A. M. Deutschbauer· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersPhysiology

L. J. Hall

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

A mutant fitness compendium in Bifidobacteria reveals molecular determinants of colonization and host-microbe interactions

A. L. Shiver, J. Sun, R. Culver, A. Violette, C. Wynter, M. Nieckarz, S. P. Mattiello, P. K. Sekhon, L. Friess, H. K. Carlson, D. Wong, S. K. Higginbottom, M. Weglarz, W. Wang, B. D. Knapp, , K. C. Huang

The paper creates a mutant fitness compendium for Bifidobacterium breve to identify molecular factors affecting colonization and host-microbe interactions.

bioRxiv · Aug 29, 2023 · PreprintMicrobiology

Maternal microbiota Bifidobacterium promotes placental morphogenesis, nutrient transport and fetal growth in mice

J. Lopez-Tello, Z. Schofield, R. Kiu, M. J. Dalby, D. van Sinderen, G. Le Gall, A. N. Sferruzzi-Perri, L. J. Hall

This study shows that Bifidobacterium breve UCC2003 in the maternal gut microbiota promotes placental development, nutrient transport, and fetal growth in mice.

Cellular and Molecular Life Sciences · Jun 28, 2022Peer-reviewedPhysiology

Analysis of selection methods to develop novel phage therapy cocktails against antimicrobial resistant clinical isolates of bacteria

M. E. Haines, F. E. Hodges, J. Y. Nale, J. Mahony, D. van Sinderen, J. Kaczorowska, B. Alrashid, M. Akter, N. Brown, D. Sauvageau, T. Sicheritz-Ponten, A. M. Thanki, A. Millard, E. E. Galyov, M. R. Clokie

This paper evaluates selection methods for developing phage cocktails against ESBL-producing bacteria, finding that planktonic killing assays are effective and efficient for identifying effective phages.

bioRxiv · Oct 13, 2020Microbiology

Bifidobacterium breve UCC2003 exopolysaccharide modulates the early life microbiota by acting as a dietary substrate

D. Puengel, A. Treveil, M. J. Dalby, S. Caim, I. J. Colquhoun, C. Booth, J. Ketskemety, T. Korcsmaros, D. van Sinderen, M. A. Lawson, L. J. Hall

This study shows that Bifidobacterium breve UCC2003 exopolysaccharide (EPS) alters infant microbiota and metabolite profiles by serving as a nutrient substrate.

Nutrients · Mar 29, 2020Peer-reviewedMicrobiology

Bifidobacterium breve UCC2003 induces a distinct global transcriptomic programme in neonatal murine intestinal epithelial cells

R. Kiu, A. Treveil, L. C. Harnisch, S. Caim, C. Leclaire, D. van Sinderen, T. Korcsmaros, L. J. Hall

This study shows that Bifidobacterium breve UCC2003 significantly alters the transcriptome of neonatal intestinal epithelial cells, enhancing cell replication, differentiation, and growth.

bioRxiv · Mar 27, 2020Immunology