Author

D. Y. Gui

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:metabolomics· 3 Research Focus:metabolism & bioenergetics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

M. G. Vander Heiden· 3 shared A. Muir· 2 shared C. A. Lewis· 2 shared L. V. Danai· 2 shared A. Ali· 1 shared A. Luengo· 1 shared A. Naamati· 1 shared B. T. Do· 1 shared

Activity by Year

2017-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersBiochemistry

M. G. Vander Heiden

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3 papers

Recent·Most cited

Increased demand for NAD+ relative to ATP drives aerobic glycolysis

A. Luengo, Z. Li, D. Y. Gui, L. B. Sullivan, M. Zagorulya, B. T. Do, R. Ferriera, A. Naamati, A. Ali, C. A. Lewis, C. J. Thomas, S. Spranger, N. J. Matheson, M. G. Vander Heiden

The paper shows that increased NAD+ demand relative to ATP demand drives aerobic glycolysis by impairing NAD+ regeneration and promoting fermentation.

bioRxiv · Jun 8, 2020Biochemistry

Quantification of microenvironmental metabolites in murine cancer models reveals determinants of tumor nutrient availability

M. R. Sullivan, L. V. Danai, C. A. Lewis, S. H. Chan, D. Y. Gui, T. Kunchok, E. A. Dennstedt, M. G. Vander Heiden, A. Muir

The paper quantifies microenvironmental metabolites in murine cancer models and identifies factors affecting tumor nutrient availability.

bioRxiv · Jan 3, 2019Cancer Biology

Environmental cystine drives glutamine anaplerosis and sensitizes cells to glutaminase inhibition

A. Muir, L. V. Danai, D. Y. Gui, C. Y. Waingarten, M. G. Vander Heiden

The paper shows that environmental cystine levels influence glutamine anaplerosis and glutaminase dependence in cancer cells.

bioRxiv · Apr 11, 2017Biochemistry