Author

Sally A. Sharpe

UK Health Security AgencyORCID 0000-0002-7014-7660Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Organism:non-human primate· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1

Frequent Co-Authors

Andrew WhiteiD· 2 shared Alex LookiD· 1 shared Ali RoghanianiD· 1 shared Andrew Chancellor· 1 shared Anele GelaiD· 1 shared Bruno LinclauiD· 1 shared Daniel J. Burns· 1 shared Frank A. W. VerreckiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersImmunology

Andrew WhiteORCID

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2 papers

Recent·Most cited

Ligand-responsive groove remodelling in human and macaque CD1d reveals a conserved MHC-like gating mechanism

Daniel J. Burns, Alex Look, Steven Turner, Martin Maly, Oliver J. Melling, Kinga Niedobecka, Rita Szoke‐Kovacs, Hatice Nurdan Aksoy Kilinc, Richard J. Suckling, Andrew Chancellor, Mariolina Salio, Andrew White, Sally A. Sharpe, Ali Roghanian, Bruno Linclau, , Salah Mansour

This study determines the crystal structures of human and macaque CD1d bound to -GalCer, revealing conserved ligand-responsive conformational flexibility at Phe84 that modulates antigen presentation.

bioRxiv · Dec 25, 2025 · PreprintImmunology

Mtb specific HLA-E restricted T cells are induced during Mtb infection but not after BCG administration in non-human primates and humans

Linda Voogd, Marjolein van Wolfswinkel, Iman Satti, Andrew White, Karin Dijkman, Anele Gela, Krista E. van Meijgaarden, Kees L. M. C. Franken, Julia L. Marshall, Tom H. M. Ottenhoff, Thomas J. Scriba, Helen McShane, Sally A. Sharpe, Frank A. W. Verreck, Simone A. Joosten

Vaccines · Oct 1, 2024Peer-reviewedImmunology