Author

David Hoyos

Memorial Sloan Kettering Cancer Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

Benjamin D. GreenbaumiD· 2 shared A Dinh Le· 1 shared Abigail G. DoucetteiD· 1 shared Alexander W. CharneyiD· 1 shared Ania WajnbergiD· 1 shared Anna KaminskaiD· 1 shared Anupma NayakiD· 1 shared Arnold J. LevineiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersGenetics

Benjamin D. GreenbaumORCID

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2 papers

Recent·Most cited

Distinct genomic and immunologic tumor evolution in germline TP53-driven breast cancers

Nabamita Boruah, David Hoyos, Renyta Moses, Ryan M. Hausler, Heena Desai, A Dinh Le, Madeline Good, Gregory Kelly, Ashvathi Raghavakaimal, Maliha N Tayeb, Mohana Narasimhamurthy, Abigail G. Doucette, Peter Edward Gabriel, Michael D. Feldman, Jinae Park, , Kara N. Maxwell

This study compares genomic and immunologic features of germline TP53-driven breast cancers to sporadic breast cancers, finding distinct patterns of genomic instability and immune infiltration.

Nature Communications · May 21, 2026Peer-reviewedGenetics

T cell epitope mapping reveals immunodominance of evolutionarily conserved regions within SARS-CoV-2 proteome.

Cansu Cimen Bozkus, Matthew Brown, Leandra G. Velazquez, Marcus Thomas, Eric A. Wilson, Timothy J. O’Donnell, Anna Kaminska, Denis Ruchnewitz, Douglas Geertz, Yonina Bykov, Julia Kodysh, Kasopefoluwa Y. Oguntuyo, Vladimir Roudko, David Hoyos, Komal Srivastava, , Nina Bhardwaj

The paper maps T cell epitopes in SARS-CoV-2, showing that immunodominant regions are conserved across variants and important for immune surveillance.

iScience · Jul 2, 2025Peer-reviewedImmunology