Combinatorial microRNA activity is essential for the transition of pluripotent cells from proliferation into dormancy
Dhanur P. Iyer, Lambert Moyon, Lars Wittler, Chieh-Yu Cheng, Francisca R. Ringeling, Stefan Canzar, Annalisa Marsico, Aydan Bulut-Karslıoğlu
The paper shows that microRNA activity is essential for early mouse embryos to transition into diapause, with miRNAs regulating gene expression and linking mTOR activity to miRNA biogenesis.
bioRxiv · Dec 20, 2023Molecular Biology