Author

Sneha Somasekar

University of California, San Francisco

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 3 Epidemiology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Assay:whole-genome sequencing· 3 Approach:experimental assay· 2 Assay:metagenomics· 2 Research Focus:phylogenetics / evolution· 2 Research Focus:variant calling· 2 Organism:bacteria (other)· 1

Frequent Co-Authors

Charles Y Chiu· 2 shared Charles Y. ChiuiD· 2 shared Doug Stryke· 2 shared Guixia Yu· 2 shared Scot FedermaniD· 2 shared A. C. F. S. Santelli· 1 shared Aakrosh RataniD· 1 shared Aaron S Burton· 1 shared

Activity by Year

2015-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersGenomics

Charles Y Chiu

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Author profile →

5 papers

Recent·Most cited

Human ACE2 receptor polymorphisms predict SARS-CoV-2 susceptibility

Kushal Suryamohan, Devan C. Diwanji, Eric W. Stawiski, Ravi Kr Gupta, Shane Miersch, Jiang Liu, Chao Chen, Ying-Ping Jiang, Frédéric A. Fellouse, J. Fah Sathirapongsasuti, Patrick K. Albers, Deepak Tanneeru, Reza Saberianfar, Aakrosh Ratan, Gavin Washburn, , Somasekar Seshagiri

This study identifies ACE2 receptor polymorphisms that may influence susceptibility to SARS-CoV-2 by altering the interaction between ACE2 and the viral S-protein.

Communications Biology · Apr 12, 2021Peer-reviewedGenetics

Epidemic establishment and cryptic transmission of Zika virus in Brazil and the Americas

Nuno Rodrigues Faria, Joshua Quick, Ingra Morales Claro, Julien Thézé, Jhennifer Guimarães Lourenço de Jesus, Marta Giovanetti, Moritz U. G. Kraemer, Sarah Catherine Hill, Allison Black, Antônio Charlys da Costa, L.C. Franco, Marcelo Sousa Silva, Chieh‐Hsi Wu, Jayna Raghwani, Simon Cauchemez, , Oliver G. Pybus

The paper uses ZIKV genomes to estimate the origin and spread of Zika virus in Brazil and the Americas, providing a timeframe for baseline microcephaly rates.

bioRxiv · Mar 27, 2017 · PreprintGenomics

Nanopore DNA Sequencing and Genome Assembly on the International Space Station

Sarah L Castro-Wallace, Charles Y Chiu, Kristen K John, Sarah E Stahl, Kathleen H Rubins, Alexa B. R. McIntyre, Jason P Dworkin, Mark L Lupisella, David J Smith, Douglas J Botkin, Timothy A Stephenson, Sissel Juul, Daniel J Turner, Fernando Izquierdo, Scot Federman, , Aaron S Burton

This study evaluates nanopore sequencing performance on the ISS, showing no performance decrease and successful genome assembly of bacterial and mammalian samples.

bioRxiv · Sep 27, 2016Genomics

Discovery of a persistent Zika virus lineage in Bahia, Brazil

Samia N. Naccache, Julien Thézé, Silvia I. Sardi, Sneha Somasekar, Alexander L. Greninger, Antonio C. Bandeira, Gubio S. Campos, Laura B. Tauro, Nuno R. Faria, Oliver G. Pybus, Charles Y. Chiu

The paper identifies a persistent Zika virus lineage in Bahia, Brazil, using metagenomic sequencing and phylogenetic analysis.

bioRxiv · Apr 24, 2016 · PreprintEpidemiology

Rapid metagenomic identification of viral pathogens in clinical samples by real-time nanopore sequencing analysis

Alex L Greninger, Samia N Naccache, Scot Federman, Guixia Yu, Placide Mbala, Vanessa Bres, Jerome Bouquet, Doug Stryke, Sneha Somasekar, Jeffrey Linnen, Roger Dodd, Prime Mulembakani, Bradley Schneider, Jean-Jacques Muyembe, Susan Stramer, Charles Y Chiu

This study uses real-time nanopore sequencing and a new pipeline to rapidly detect viral pathogens in clinical samples with high accuracy.

Genome Medicine · Sep 29, 2015Peer-reviewedGenomics