R. Zenobi

Prototyping of a lateral flow assay based on monoclonal antibodies for detection of Bothrops venoms

This paper describes a prototype lateral flow assay using monoclonal antibodies to detect Bothrops venoms, achieving a limit of detection of 8.0 ng/mL in serum and 9.5 ng/mL in urine.

Discovery of a broadly-neutralizing human antibody that can rescue mice challenged with neurotoxin-rich snake venoms

This paper describes the discovery of a broadly-neutralizing human antibody effective against multiple snake venoms, demonstrating its therapeutic potential in mice.

Metabolic reconstitution by a gnotobiotic microbiota varies over the circadian cycle

This study shows that a gnotobiotic microbiota affects metabolic processes differently depending on the circadian cycle, influencing energy balance and substrate utilization.

Hallmarks of Alpha- and Betacoronavirus non-structural protein 7+8 complexes

This study determines the stoichiometry and topology of nsp7+8 complexes from seven coronaviruses using mass spectrometry and biophysical techniques, revealing three clustering groups with distinct assembly patterns.

Occurrence and stability of hetero-hexamer associations formed by β-carboxysome CcmK shell components

This study investigates the formation and stability of hetero-hexamer associations among CcmK proteins in Synechocystis sp. PCC6803 carboxysome shells, revealing structural segregation and functional implications.

Thermal Denaturation of DNA G-Quadruplexes and their Complexes with Ligands: Thermodynamic Analysis of the Multiple States Revealed by Native Mass Spectrometry

This study uses native mass spectrometry to analyze the thermodynamics of G-quadruplex DNA denaturation and ligand binding, revealing enthalpic and entropic contributions to stability and ligand specificity.