Author

B. W.-Y. Mok

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 5 Organism:mouse· 4 Research Focus:drug response / drug discovery· 2 Assay:bulk RNA-seq· 1 Organism:human· 1 Organism:zebrafish· 1

Frequent Co-Authors

H. Chen· 4 shared K.-Y. Yuen· 4 shared P. Wang· 4 shared S.-Y. Lau· 4 shared A. J. Zhang· 3 shared K. K.-W. To· 3 shared A. C.-Y. Lee· 2 shared B. Zhou· 2 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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Curved chords = mutual co-authorship

4 shared papersImmunology

H. Chen

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

An elite broadly neutralizing antibody protects SARS-CoV-2 Omicron variant challenge

B. Zhou, R. Zhou, J. F.-W. Chan, M. Luo, Q. Peng, S. Yuan, B. W.-Y. Mok, B. Chen, P. Wang, V. K.-M. Poon, H. Chu, C. C.-S. Chan, J. O.-L. Tsang, C. C.-Y. Chan, K.-K. Au, , Z. Chen

This study identifies a broadly neutralizing antibody, ZCB11, effective against SARS-CoV-2 Omicron and Delta variants, showing protection in hamsters.

bioRxiv · Jan 5, 2022 · PreprintImmunology

Nasal prevention of SARS-CoV-2 infection by intranasal influenza-based boost vaccination

R. Zhou, P. Wang, Y.-C. Wong, H. Xu, S.-Y. Lau, L. Liu, B. W.-Y. Mok, Q. Peng, N. Liu, S. Deng, R. C.-Y. Tam, H. Huang, A. J. Zhang, D. Zhou, B. Zhou, , Z. Chen

This study shows that intranasal influenza-based boost vaccination enhances mucosal and systemic immunity against SARS-CoV-2, effectively preventing infection in both upper and lower respiratory systems.

bioRxiv · Oct 21, 2021 · PreprintImmunology

Low dose inocula of SARS-CoV-2 B.1.1.7 variant initiate more robust infections in the upper respiratory tract of hamsters than earlier D614G variants

B. W.-Y. Mok, H. Liu, S.-Y. Lau, S. D. Deng, S. Liu, R. C.-Y. Tam, T. T.-L. Ng, J. S.-L. Leung, P. Wang, K. K.-W. To, J. F.-W. Chan, K.-H. Chan, K.-Y. Yuen, G. K.-H. Siu, H. Chen

This study shows that the B.1.1.7 SARS-CoV-2 variant replicates and sheds more efficiently in hamsters' nasal cavities than earlier D614G variants with lower doses and shorter exposure.

bioRxiv · Apr 19, 2021 · PreprintMicrobiology

Topoisomerase 1 inhibition therapy protects against SARS-CoV-2-induced inflammation and death in animal models.

J. S. Y. Ho, B. W.-Y. Mok, L. Campisi, T. Jordan, S. Yildiz, S. Parameswaran, J. A. Wayman, N. N. Gaudreault, D. A. Meekins, S. V. Indran, I. Morozov, J. D. Trujillo, Y. S. Fstkchyan, R. Rathnasinghe, Z. Zhu, , Jeya

This study shows that Top1 inhibition with Topotecan reduces SARS-CoV-2-induced inflammation and mortality in animal models.

bioRxiv · Dec 1, 2020 · PreprintMicrobiology

Pathogenicity, immunogenicity, and protective ability of an attenuated SARS-CoV-2 variant with a deletion at the S1/S2 junction of the spike protein

P. Wang, S.-Y. Lau, S. Deng, P. Chen, B. W.-Y. Mok, A. J. Zhang, A. C.-Y. Lee, K.-H. Chan, W. Song, K. K.-W. To, J. F.-W. Chen, K.-Y. Yuen, H. Chen

This study characterizes an attenuated SARS-CoV-2 variant with a deletion at the S1/S2 junction, showing reduced pathogenicity and immunogenicity but strong protective immunity.

bioRxiv · Aug 24, 2020 · PreprintMicrobiology