Author

E. M. Kwong

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

S. L. Leibel· 3 shared A. E. Clark· 2 shared B. A. Croker· 2 shared C. J. Nowell· 2 shared R. N. McVicar· 2 shared A. Alvarado· 1 shared A. Denardo· 1 shared A. F. Carlin· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersImmunology

S. L. Leibel

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

EGFR+ lung adenocarcinomas coopt alveolar macrophage metabolism and function to support EGFR signaling and growth

A. Kuhlmann-Hogan, T. Cordes, Z. Xu, K. Traina, C. Robles-Oteiza, D. Ayeni, E. M. Kwong, S. Levy, M. Nobari, G. Z. Cheng, R. J. Shaw, S. L. Leibel, C. Metallo, K. Politi, S. M. Kaech

This study shows EGFR-mutant lung adenocarcinomas exploit alveolar macrophage metabolism via GM-CSF--PPARγ signaling to support tumor growth and EGFR signaling, suggesting new therapeutic strategies combining statins and PPARγ inhibition.

bioRxiv · Apr 15, 2023 · PreprintImmunology

The lung employs an intrinsic surfactant-mediated inflammatory response for viral defense

S. L. Leibel, R. N. McVicar, R. Murad, E. M. Kwong, A. E. Clark, A. Alvarado, B. A. Grimmig, R. Nuryyev, R. E. Young, J. C. Lee, W. Peng, Y. P. Zhu, E. Griffis, C. J. Nowell, B. James, , E. Y. Snyder

This study shows that surfactant proteins mediate an intrinsic inflammatory response in the lung to defend against SARS-CoV-2 infection.

bioRxiv · Jan 26, 2023 · PreprintImmunology

The Prolyl-tRNA Synthetase Inhibitor Halofuginone Inhibits SARS-CoV-2 Infection

D. R. Sandoval, T. Mandel Clausen, C. Nora, J. A. Magida, A. P. Cribbs, A. Denardo, A. E. Clark, A. F. Garretson, J. K. C. Coker, A. Narayanan, S. A. Majowicz, M. Philpott, C. Johansson, J. E. Dunford, C. B. Spliid, , Mazitsch

This study identifies halofuginone as a potent inhibitor of SARS-CoV-2 infection and replication by reducing heparan sulfate biosynthesis and suppressing viral replication.

bioRxiv · Mar 22, 2021 · PreprintMicrobiology