Author

E. Yung

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

C. M. Rive· 2 shared G. Sharma· 2 shared L. Dreolini· 2 shared R. A. Holt· 2 shared S. D. Brown· 2 shared C. G. May· 1 shared C. May· 1 shared C. S. Hughes· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

C. M. Rive

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A Synthetic Cytotoxic T cell Platform for Rapidly Prototyping TCR Function

G. Sharma, J. Round, F. Teng, Z. Ali, C. May, E. Yung, R. Holt

This paper introduces a synthetic cytotoxic T cell platform for rapidly prototyping TCR function, demonstrating successful antigen-specific responses and preservation of antigen-presenting cells.

bioRxiv · Nov 20, 2023Immunology

Recombinant T cell receptors specific for HLA-A*02:01-restricted neoepitopes containing KRAS codon 12 hotspot mutations

C. M. Rive, E. Yung, C. S. Hughes, S. D. Brown, G. Sharma, L. Dreolini, N. M. Mawji, C. Warren, J. Karasinska, J. M. Loree, D. T. Yapp, G. B. Morin, D. J. Renouf, D. F. Schaeffer, S. Turcotte, R. A. Holt

The paper identifies and characterizes T cell receptors specific for HLA-A*02:01-restricted KRAS codon 12 mutations in cancer, showing their reactivity and cytotoxic activity against tumor cells.

bioRxiv · Jun 15, 2020 · PreprintImmunology

Selective B cell depletion upon intravenous infusion of replication-incompetent anti-CD19 CAR lentivirus

C. M. Rive, E. Yung, L. Dreolini, S. D. Brown, C. G. May, D. J. Woodsworth, R. A. Holt

This study shows that IV infusion of anti-CD19 CAR lentiviral vectors leads to persistent CAR-T cell expansion and complete B cell depletion in mice.

bioRxiv · May 15, 2020Immunology