Structural basis for membrane remodelling by the AP5:SPG11-SPG15 complex
X. Mai, Y. Wang, X. Wang, M. Liu, F. Teng, Z. Liu, M.-Y. Su, G. Stjepanovic
This study determines the structure of the AP5:SPG11-SPG15 complex and shows it binds PI3P, senses membrane curvature, and drives membrane remodeling in vitro.
bioRxiv · Jun 14, 2024 · PreprintBiochemistry