Author

E. Z. WOLF

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

D. J. Wilson· 2 shared A. J. Lamberto· 1 shared A. M. Barsotti· 1 shared A. Pon· 1 shared A. W. Stamford· 1 shared B. Raught· 1 shared B. Wilson· 1 shared C. Arrowsmith· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBiochemistry

D. J. Wilson

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2 papers

Recent·Most cited

Recruitment of FBXO22 for Targeted Degradation of NSD2

D. Y. Nie, J. R. Tabor, J. Li, M. Kutera, J. St-Germain, R. P. Hanley, E. Z. WOLF, E. Paulakonis, T. M. G. Kenney, S. Duan, S. Shrestha, D. D. Owens, A. Pon, M. Szewczyk, A. J. Lamberto, , C. Arrowsmith

This paper describes a targeted protein degradation strategy using UNC8732 to recruit FBXO22 for NSD2 degradation, leading to growth suppression and reversal of drug resistance in leukemia cells.

bioRxiv · Nov 1, 2023Biochemistry

Small molecule screen identifies non-catalytic USP3 chemical handle

M. K. Mann, E. Z. WOLF, M. Silva, B. Wilson, D. J. Wilson, R. J. Harding, M. Schapira

The paper identifies a small molecule ligand for the ZnF-UBD of USP3 with a KD of 14 µM, which could serve as a starting point for developing DUBTACs.

bioRxiv · Mar 1, 2023Biochemistry