Transcription factors form a ternary complex with NIPBL/MAU2 to localize cohesin at enhancers
Grégory Fettweis, Kaustubh Wagh, Diana A. Stavreva, Alba Jiménez‐Panizo, Sohyoung Kim, Michelle Lion, Andrea Alegre‐Martí, Lorenzo Rinaldi, Thomas A. Johnson, Elise Gilson, Manan Krishnamurthy, Li Wang, David A. Ball, Tatiana Karpova, Arpita Upadhyaya, , Gordon L. Hager
The paper identifies LxxLL motifs in NIPBL that regulate its interaction with MAU2 and steroid receptors, forming a ternary complex with GR to facilitate enhancer localization of cohesin.
Nucleic Acids Research · May 10, 2025Peer-reviewedMolecular Biology