Local translation controls early reactive changes in perisynaptic astrocyte processes at pre-symptomatic stages of Alzheimers disease
Katia Avila‐Gutierrez, María-Angeles Carrillo-de Sauvage, Noémie Depret, Marc Oudart, Robin Thompson, Rodrigo Alvear‐Perez, Yiannis Poulot-Becq-Giraudon, Esther Kozlowski, Héloïse Monnet, Philippe Mailly, Valentin Garcia, Laurent Jourdren, Alexandre Lucas, Alexis‐Pierre Bemelmans, Hélène Hirbec, , Martine Cohen‐Salmon
The paper identifies astrocyte perisynaptic processes as sites of early translational dysregulation in Alzheimer's disease, linking it to synaptic dysfunction and disease initiation.
Neurobiology of Disease · Jul 9, 2026Peer-reviewedNeuroscience