Author

F. Allen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Assay:CRISPR screen· 1

Frequent Co-Authors

A. Crayton· 1 shared A. Friedman· 1 shared A. Moroz· 1 shared A. Mychalowych· 1 shared A. N. Shami· 1 shared A. Tsherniak· 1 shared A. Vanderbeck· 1 shared C. E. Keegan· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCell Biology

A. Crayton

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

How long does it take to cue a Pseudomonas aeruginosa chronic infection phenotype in the lab? Insights from transcriptome analysis in a cystic fibrosis lung model.

N. E. Harrington, F. Allen, R. Garcia-Maset, F. Harrison

This study investigates how quickly Pseudomonas aeruginosa develops chronic infection traits in a CF lung model over 7 days, showing increased antibiotic tolerance and biofilm formation.

bioRxiv · Jun 30, 2022 · PreprintMicrobiology

Differential impact of a dyskeratosis congenita mutation in TPP1 on mouse hematopoiesis and germline

J. V. Graniel, K. Bisht, A. Friedman, J. White, E. Perkey, A. Vanderbeck, A. Moroz, L. J. Carrington, J. D. Brandstadter, F. Allen, A. N. Shami, P. Thomas, A. Crayton, M. Manzor, A. Mychalowych, , J. Nandakumar

This study examines the impact of a dyskeratosis congenita mutation in TPP1 on mouse hematopoiesis and germline, finding progressive telomere erosion and infertility without bone marrow failure.

Life Science Alliance · Oct 13, 2021Peer-reviewedCell Biology

The Sec1/Munc18 protein Vps45 holds the Qa-SNARE Tlg2 in an open conformation

T. Eisemann, F. Allen, K. Lau, G. R. Shimamura, P. D. Jeffrey, F. M. Hughson

This paper presents the structure of the Vps45–Tlg2 SM–Qa-SNARE complex, showing Vps45 holds Tlg2 in an open conformation, distinct from the closed conformation seen in Munc18-1–syntaxin 1 complexes.

bioRxiv · Jul 1, 2020Cell Biology

Agreement between two large pan-cancer CRISPR-Cas9 gene dependency datasets

J. M. Dempster, C. Pacini, S. Pantel, F. M. Behan, T. Green, J. Krill-Burger, C. M. Beaver, S. T. Younger, V. Zhivich, H. Najgebauer, F. Allen, E. Goncalves, R. Shepherd, J. G. Doench, K. Yusa, , A. Tsherniak

This study compares two large pan-cancer CRISPR-Cas9 screens, finding high concordance in gene dependencies despite differences in protocols and reagents.

bioRxiv · Jun 4, 2019Cancer Biology