Author

C. Pacini

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1 Assay:CRISPR screen· 1

Frequent Co-Authors

A. Tsherniak· 1 shared B.-K. Koo· 1 shared C. M. Beaver· 1 shared C. R. Bradshaw· 1 shared D. E. Root· 1 shared D. Ivanoiu· 1 shared E. Canale· 1 shared E. Goncalves· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCancer Biology

A. Tsherniak

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Genetic and epigenetic driven variation in regulatory regions activitycontribute to adaptation and evolution under endocrine treatment

N. Slaven, R. Lopes, E. Canale, D. Ivanoiu, C. Pacini, I. A. Monteiro Barbosa, M. Bleu, S. Bravaccini, S. Ravaioli, M. V. Dieci, G. Pruneri, G. Galli, I. Barozzi, L. Magnani

This study identifies non-coding DNA alterations in hormone-dependent breast cancer that contribute to endocrine therapy resistance and disease progression.

bioRxiv · Feb 15, 2022 · PreprintCancer Biology

Loss of RNF43/ZNRF3 predisposes to Hepatocellular carcinoma by impairing liver regeneration and altering liver fat metabolism

G. Mastrogiovanni, C. Pacini, S. Kakava, R. Arnes-Benito, C. R. Bradshaw, S. Davies, K. Saeb-Parsy, B.-K. Koo, M. Huch

This study shows that loss of RNF43/ZNRF3 leads to liver cancer by disrupting lipid metabolism and impairing liver regeneration in mice, with similar effects observed in human patients.

bioRxiv · Sep 25, 2020 · PreprintCancer Biology

Agreement between two large pan-cancer CRISPR-Cas9 gene dependency datasets

J. M. Dempster, C. Pacini, S. Pantel, F. M. Behan, T. Green, J. Krill-Burger, C. M. Beaver, S. T. Younger, V. Zhivich, H. Najgebauer, F. Allen, E. Goncalves, R. Shepherd, J. G. Doench, K. Yusa, , A. Tsherniak

This study compares two large pan-cancer CRISPR-Cas9 screens, finding high concordance in gene dependencies despite differences in protocols and reagents.

bioRxiv · Jun 4, 2019Cancer Biology