F. Andreoni

Screening clinical Candida albicans isolates for invasiveness by mimicking the human environment

The paper screens Candida albicans isolates for invasiveness by assessing filamentation patterns under simulated host conditions.

C-di-AMP levels modulate Staphylococcus aureus cell wall thickness as well as virulence and contribute to antibiotic resistance and tolerance

This study shows that high c-di-AMP levels in Staphylococcus aureus increase cell wall thickness and antibiotic resistance, while reducing cell size and antioxidant production.

Group A Streptococcus strains causing meningitis without distinct invasive phenotype

This study compares GAS strains from meningitis and otitis cases, finding no distinct invasive traits associated with meningitis.

Group A Streptococcus antibiotic tolerance in necrotizing fasciitis

This study shows that Group A Streptococcus (GAS) persisters are present in tissue from necrotizing fasciitis patients and contribute to antibiotic treatment failure.

Intervertebral disc cell chondroptosis elicits neutrophil response in Staphylococcus aureus spondylodiscitis

This study investigates S. aureus spondylodiscitis by combining clinical data and an ex vivo porcine model, showing IVD cell death and neutrophil recruitment.

Limited adaptive evolution of Staphylococcus aureus during transition from colonization to invasive infection

The paper compares phenotypic and genotypic profiles of S. aureus colonizing and invasive isolates, finding limited genetic evolution and similar traits, with barrier disruption as key to disease progression.

Assessing antibiotic tolerance of Staphylococcus aureus derived directly from patients by the Replica Plating Tolerance Isolation System- REPTIS

This study evaluates the REPTIS method for detecting antibiotic tolerance in S. aureus isolates from patients, finding regrowth patterns linked to antibiotic targets and patient characteristics.