Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
5 papers
Recent·Most cited
W. J. Woolley, Y. Obata, K. Martin, C. Acevedo
This study links reduced bone toughness in T2DM rats to microstructural changes in canals and osteocyte lacunae, along with AGEs accumulation.
bioRxiv · Mar 7, 2023 · PreprintBioengineering
T. A. Schweizer, F. Andreoni, C. Acevedo, T. C. Scheier, I. Heggli, E. Marques Maggio, N. Eberhard, S. D. Brugger, S. Dudli, A. S. Zinkernagel
This study investigates S. aureus spondylodiscitis by combining clinical data and an ex vivo porcine model, showing IVD cell death and neutrophil recruitment.
bioRxiv · Jan 31, 2022Immunology
S. Mairpady Shambat, A. Gomez-Mejia, T. A. Schweizer, M. Huemer, C.-C. Chang, C. Acevedo, J. Bergada Pijuan, C. Vulin, N. Miroshnikova, D. A. Hofmanner, P. D. Wendel Garcia, M. P. Hilty, P. K. Buehler, R. A. Schuepbach, S. D. Brugger, A. S. Zinkernagel
This study shows that severe hypercytokinemia in COVID-19 patients impairs neutrophil and monocyte function against bacterial challenges, leading to reduced microbicidal capacity and altered receptor signaling.
PLOS Pathogens · Jan 10, 2022Peer-reviewedImmunology
T. A. Schweizer, S. Mairpady Shambat, C. Vulin, S. Hoeller, C. Acevedo, M. Huemer, A. Gomez-Mejia, C.-C. Chang, J. Baum, S. Hertegonne, E. Hitz, D. A. Hofmaenner, P. K. Buehler, H. Moch, R. A. Schuepbach, , A. S. Zinkernagel
The paper shows that in critically ill COVID-19 patients, dysregulated Fas signaling leads to increased RIPK1-driven necroptosis in neutrophils, contributing to disease severity.
bioRxiv · Mar 19, 2021 · PreprintImmunology
C. M. Mazur, J. J. Woo, C. S. Yee, A. J. Fields, C. Acevedo, K. N. Bailey, T. W. Fowler, J. C. Lotz, A. Dang, A. Kuo, T. P. Vail, T. Alliston
This study shows that suppressed osteocyte perilacunar/canalicular remodeling causes osteoarthritis by impairing cartilage homeostasis in humans and mice.
bioRxiv · Jan 31, 2019Physiology