F. He

Shotgun metagenomics reveals an enrichment of potentially cross-reactive bacterial epitopes in ankylosing spondylitis patients, as well as the effects of TNFi therapy and the host’s genotype upon microbiome composition

The paper uses shotgun metagenomics to analyze the gut microbiome in AS patients, finding enriched bacterial epitopes linked to HLA-B27 and effects of TNFi therapy and host genotype on microbiome composition.

Combinatorial morphogenetic and mechanical cues to mimic bone development for defect repair

The paper demonstrates that engineered human mesenchymal stem cell condensations with dual BMP-2 and TGF-β1 promote functional healing of critical-sized femoral defects via endochondral ossification, with healing rate and extent dependent on in vivo mechanical environment.

Arabidopsis species deploy distinct strategies to cope with drought stress

This study compares drought stress responses in three Arabidopsis species, finding distinct survival strategies involving avoidance, tolerance, and recovery mechanisms.

Assortment of flowering time and immunity alleles in natural Arabidopsis thaliana populations suggests immunity and vegetative lifespan strategies coevolve

The paper shows that in Arabidopsis thaliana, immunity gene expression correlates with flowering time, suggesting coevolution of immunity and vegetative lifespan strategies.

Defining the Layers of a Sensory Cilium with STORM and Cryo-Electron Nanoscopies

The paper uses advanced microscopy techniques to define substructures within sensory cilia and examines the effects of ciliopathy proteins on protein distribution.

Convergence of Wnt, Growth Factor and Trimeric G protein signals on Daple

This study identifies Daple as a convergence point for Wnt, growth factor, and G-protein signaling in cancer, showing its role in tumor progression and poor prognosis in colorectal cancer.