Author

F. M. Barriga

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell-cell communication· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1

Frequent Co-Authors

D. Alonso-Curbelo· 3 shared D. Pe'er· 3 shared R. Chaligne· 3 shared S. W. Lowe· 3 shared A. N. Wuest· 2 shared C. A. Iacobuzio-Donahue· 2 shared G. Livshits· 2 shared I. Masilionis· 2 shared

Activity by Year

2022-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

D. Alonso-Curbelo

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4 papers

Recent·Most cited

Metastatic site influences driver gene function in pancreatic cancer

K. M. Tsanov, F. M. Barriga, Y.-J. Ho, D. Alonso-Curbelo, G. Livshits, R. P. Koche, T. Baslan, J. Simon, S. Tian, A. N. Wuest, W. Luan, J. E. Wilkinson, I. Masilionis, N. Dimitrova, C. A. Iacobuzio-Donahue, , S. W. Lowe

This study shows that metastatic site influences the function of driver genes like SMAD4 in pancreatic cancer, with organ-specific epigenetic states affecting tumor growth.

bioRxiv · Mar 17, 2024 · PreprintCancer Biology

Chromosome 9p21.3 Coordinates Cell Intrinsic and Extrinsic Tumor Suppression

S. Lowe, F. M. Barriga, K. M. Tsanov, Y. J. Ho, N. Sohail, A. Zhang, T. Baslan, A. N. Wuest, I. Del Priore, B. Meskauskaite, G. Livshits, D. Alonso-Curbelo, J. Simon, A. Chaves-Perez, D. Bar-Sagi, , D. Pe'er

The paper investigates how 9p21.3 deletions in cancer disable both cell intrinsic and extrinsic tumor suppression by co-deleting CDKN2A/B and type I interferons, leading to immune evasion and metastasis.

bioRxiv · Aug 22, 2022 · PreprintCancer Biology

Epigenetic plasticity cooperates with emergent cell-cell interactions to drive neoplastic tissue remodeling in the pancreas

C. Burdziak, D. Alonso-Curbelo, T. Walle, F. M. Barriga, J. Reyes, Y. Xie, Z. Zhao, C. J. Zhao, H.-A. Chen, O. Chaudhary, I. Masilionis, Z.-N. Choo, V. Gao, W. Luan, A. Wuest, , D. Pe'er

The paper uses single-cell analysis to show that epigenetic plasticity and cell-cell interactions drive tissue remodeling in early pancreatic cancer.

bioRxiv · Jul 26, 2022Cancer Biology

A new immunocompetent rectal cancer model to study radiation therapy

J. K. Kim, C. Wu, M. Del Latto, Y. Gao, S.-H. Choi, M. Kierstead, C.-E. G. Sauve, C. Firat, A. C. Perez, J. Sillanpaa, C.-T. Chen, K. E. Lawrence, P. B. Paty, F. M. Barriga, J. Shia, , J. J. Smith

This paper introduces a mouse model of rectal cancer that mimics human tumor progression and radiation response for preclinical studies.

bioRxiv · Feb 7, 2022 · PreprintCancer Biology