F. Zhang

This paper shows that within-host recombination and epistasis significantly drive molecular evolution of FMDV capsid genes, with recombination rates comparable to mutation rates.

This paper introduces DNA microscopy, a method that maps biomolecule positions without optics, using chemical reactions and sequencing to infer spatial organization.

This paper develops a platform to multiplex profile single-cell EV secretion, revealing heterogeneity in EV phenotypes and secretion patterns in OSCC cells.

This study reveals that miRNAs directly feedback-regulate their targeting machinery mRNAs, but not upstream biogenesis or downstream effector mRNAs, uncovering segment-specific feedback auto-regulation of the miRNA pathway.

The paper identifies key inflammatory cell states in RA synovial tissues using integrated single-cell and mass cytometry data from patient samples.

This paper introduces a method to identify proteins associated with a specific genomic locus in living cells without requiring specific antibodies.

The paper identifies early urinary biomarkers for astrocytoma in rats before MRI changes, using proteomic analysis of urine samples collected at different time points post-tumor induction.

This study investigates the role of the apical polar ring in Toxoplasma gondii by analyzing KinesinA and APR1, showing its structural importance for microtubule organization and parasite function.

The paper identifies two CRISPR-Cas VI-B systems with Cas13b and characterizes their RNA interference activity and regulation by Csx27 and Csx28.