L. Almeida

An efficient inducible model for the control of gene expression in renin cells

This paper develops an inducible mouse model to specifically control gene expression in renin cells, demonstrating efficient and targeted deletion of renin in adult mice without developmental effects.

Fitness adaptations of Japanese encephalitis virus in pigs following vector-free serial passaging

This study shows that serial passaging of JEV in pigs leads to fitness adaptations and amino acid changes, but not increased direct transmission.

In Vitro Inhibition of SARS-CoV-2 Infection by Bromhexine hydrochloride

This study shows bromhexine hydrochloride inhibits SARS-CoV-2 infection in vitro by targeting TMPRSS2, reducing viral entry and progeny without direct virucidal activity.

Spectral flow cytometry reveals metabolic heterogeneity in tissue macrophages

This study uses spectral flow cytometry to reveal metabolic heterogeneity in tissue macrophages across different organs and under infection conditions.

M2-polarized macrophages control LSC fate by enhancing stemness, homing, immune evasion and metabolic reprogramming

The paper shows M2-polarized macrophages promote leukemia stem cell survival by enhancing stemness, homing, immune evasion, and metabolic reprogramming.

Ribosome-targeting antibiotics impair T cell effector function and ameliorate autoimmunity by blocking mitochondrial protein synthesis