Author

G. Boland

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

A. Sahu· 2 shared J. Chen· 2 shared A. Amzallag· 1 shared A. Chaudhri· 1 shared A. Friedman· 1 shared A. Lazar· 1 shared A. Shi· 1 shared A. Singh· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCancer Biology

A. Sahu

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Enhancer Reprogramming in Melanoma Immune Checkpoint Therapy Resistance

M. Maitituoheti, A. Shi, M. Tang, L.-L. Ho, C. Terranova, K. Galani, E. Keung, C. Creasy, M. Wu, J. Chen, N. Chen, A. Singh, A. Chaudhri, N. Anvar, G. Tarantino, , K. Rai

The paper identifies enhancer-based biomarkers of resistance to anti-PD-1 therapy in melanoma and suggests enhancer blockade combined with ICB as a potential strategy to improve treatment responses.

bioRxiv · Aug 31, 2022 · PreprintCancer Biology

Altered interactions between circulating and tissue-resident CD8 T cells with the colonic mucosa define colitis associated with immune checkpoint inhibitors

M. Thomas, K. Slowikowski, K. Manakongtreecheep, P. Sen, J. Tantivit, M. Nasrallah, N. Smith, S. Ramesh, L. Zubiri, A. Tirard, B. Arnold, L. Nieman, J. Chen, T. Eisenhaure, K. Pelka, , A.-C. Villani

This study identifies altered interactions between circulating and tissue-resident CD8 T cells with the colonic mucosa in immune checkpoint inhibitor-associated colitis using single-cell RNA sequencing and other multi-omics approaches.

bioRxiv · Sep 17, 2021Immunology

Genome-wide CRISPR screens identify essential cell growth mediators in BRAF-inhibitor resistant melanoma

Z. Li, B. Wang, S. Gu, P. Jiang, A. Sahu, C.-H. Chen, T. Han, S. Shi, X. Wang, N. Traugh, H. Liu, Y. Liu, Q. Wu, M. Brown, T. Xiao, , S. Liu

The paper identifies key regulators of BRAF inhibitor resistance in melanoma using CRISPR screens and integrates multi-omics data to reveal CDK6-dependent mechanisms.

bioRxiv · Dec 16, 2019Cancer Biology

Genome-wide prediction of synthetic rescue mediators of resistance to targeted and immunotherapy

A. Sahu, J. Sang Lee, G. Zhang, Z. Wang, T. Tian, T. Moll, G. Kasumova, B. Miao, Z. Wei, N. U. Nair, O. Ponomarova, A. Friedman, A. Amzallag, P. Greninger, R. Egan, , E. Ruppin

The paper predicts synthetic rescue mediators of resistance to targeted and immunotherapy using tumor transcriptomics and survival data from 10,000 TCGA patients, validating predictions through experimental screens.

bioRxiv · Apr 8, 2018Cancer Biology