Author

G. de Haan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

A. Ausema· 1 shared A. Damaskou· 1 shared A. de Bruin· 1 shared A. E. Tijhuis· 1 shared A. F. Svendsen· 1 shared A. Mura-Meszaros· 1 shared A. Strong· 1 shared A. van den Brink· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

A. Ausema

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cancer tolerance to chromosomal instability is driven by Stat1 inactivation in vivo

M. Schubert, C. Hong, L. J. Jilderda, M. Requesens-Rueda, A. E. Tijhuis, J. E. Simon, P. L. Bakker, J. Cooper, A. Damaskou, R. Wardenaar, B. Bakker, S. Gupta, A. van den Brink, L. Andrade-Ruiz, M. H. Koster, , F. Foijer

The paper identifies Stat1 inactivation as a mechanism by which aneuploid cancers evade immune surveillance in mice and humans.

bioRxiv · Dec 3, 2021 · PreprintCancer Biology

The developmental stage of the medulloblastoma cell-of-origin restricts Hedgehog pathway usage and drug sensitivity

M. J. Smit, I. Armandari, I. Bockaj, T. E. I. Martini, W. W. Zomerman, Z. Siragna, T. G. J. Meeuwsen-de Boer, F. J. G. Scherpen, M. H. Schoots, M. Ritsema, W. F. A. den Dunnen, E. H. Hoving, J. T. M. L. Paridaen, G. de Haan, V. Guryev, S. Bruggeman

The paper shows that the developmental stage of medulloblastoma cell-of-origin affects Hedgehog pathway usage and drug sensitivity, with downstream pathway targets being more effective in infant patients.

bioRxiv · Jan 22, 2021Cancer Biology

A comprehensive transcriptome signature of murine hematopoietic stem cell aging

A. F. Svendsen, D. Yang, S. Lazare, E. Zwart, A. Mura-Meszaros, A. Ausema, B. von Eyess, G. de Haan, L. Bystrykh

The paper identifies a core transcriptional aging signature in murine hematopoietic stem cells, showing increased membrane-associated gene expression and age-related heterogeneity.

bioRxiv · Aug 10, 2020Cell Biology