Author

A. C. Colabardini

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 6 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Organism:Arabidopsis· 5 Approach:experimental assay· 4 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:gene regulatory network inference· 2 Research Focus:host-pathogen & immune response· 2 Assay:whole-genome sequencing· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

G. H. Goldman· 6 shared A. Rokas· 4 shared F. Wang· 3 shared P. A. de Castro· 3 shared R. Bastos· 3 shared T. F. dos Reis· 3 shared C. Valero· 2 shared H. A. Raja· 2 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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6 shared papersMicrobiology

G. H. Goldman

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Evolutionary origin, population diversity, and diagnostics for a cryptic hybrid pathogen

J. L. Steenwyk, S. L. Knowles, R. Bastos, C. Balamurugan, D. Rinker, M. E. Mead, C. D. Roberts, H. A. Raja, Y. Li, A. C. Colabardini, P. A. Castro, T. F. Reis, D. Canovas, R. L. Sanchez, K. Lagrou, , A. Rokas

This study identifies and characterizes the cryptic fungal pathogen Aspergillus latus, revealing its hybrid origin and developing genomic and phenotypic markers for accurate diagnosis.

bioRxiv · Jul 3, 2023 · PreprintEvolutionary Biology

Aspergillus fumigatus FhdA transcription factor is important for mitochondrial activity and codon usage regulation during the caspofungin paradoxical effect

A. C. Colabardini, N. van Rhijn, A. L. LaBella, C. Valero, F. Wang, L. Dineen, A. Rokas, G. H. Goldman

This study shows that FhdA regulates mitochondrial activity and tRNA expression in Aspergillus fumigatus during caspofungin tolerance.

bioRxiv · May 21, 2022Microbiology

Secondary metabolites produced during Aspergillus fumigatus and Pseudomonas aeruginosa biofilm formation

R. Bastos, D. Akiyama, T. F. dos Reis, A. C. Colabardini, R. S. Luperini, P. A. de Castro, R. L. Baldini, T. Pacheco Fill, G. H. Goldman

This study identifies secondary metabolites produced by Aspergillus fumigatus and Pseudomonas aeruginosa during biofilm formation in normoxia and hypoxia, revealing differences in metabolite secretion between monoculture and co-culture.

bioRxiv · Apr 25, 2022Microbiology

Every single conidium in Aspergillus fumigatus caspofungin tolerant strains are intrinsically caspofungin tolerant

C. Valero, A. C. Colabardini, P. A. de Castro, J. Amich, M. J. Bromley, G. H. Goldman

The paper investigates whether caspofungin tolerance in Aspergillus fumigatus is a population-level or individual-level trait by testing conidia from clinical isolates.

bioRxiv · Feb 17, 2022 · PreprintMicrobiology

Regulation of gliotoxin biosynthesis and protection in Aspergillus species

P. A. de Castro, M. Moraes, A. C. Colabardini, M. A. C. Horta, S. L. Knowles, H. A. Raja, N. H. Oberlies, Y. Koyama, M. Ogawa, K. Gomi, J. L. Steenwyk, A. Rokas, R. A. Goncales, C. Duarte-Oliveira, A. Carvalho, , G. H. Goldman

This study identifies conserved transcription factors and genes involved in gliotoxin protection in Aspergillus species through RNA-sequencing and deletion screening.

bioRxiv · Aug 16, 2021Microbiology

Heterogeneity in the transcriptional response of the human pathogen Aspergillus fumigatus to the antifungal agent caspofungin

A. C. Colabardini, F. Wang, Z. Dong, L. Pardeshi, M. C. Rocha, J. H. Costa, T. F. dos Reis, A. Brown, Q. Z. Jaber, M. Fridman, T. Fill, A. Rokas, I. Malavazi, K. H. Wong, G. H. Goldman

This study investigates transcriptional heterogeneity in Aspergillus fumigatus strains responding to caspofungin, identifying a core response and variable response linked to secondary metabolite biosynthesis and iron homeostasis.

bioRxiv · Jul 15, 2021Microbiology

Screening of chemical libraries for new antifungal drugs against Aspergillus fumigatus reveals the potential mechanism of action of miltefosine

T. F. dos Reis, M. A. C. Horta, A. C. Colabardini, C. M. Fernandes, L. P. Silva, R. Bastos, M. V. L. Fonseca, F. Wang, C. Martins, M. Rodrigues, C. Silva Pereira, M. Del Poeta, K. H. Wong, G. H. Goldman

This study screens 1,127 compounds against Aspergillus fumigatus, identifies miltefosine as fungicidal, and reveals RmiA as a transcription factor regulating sphingolipid biosynthesis involved in miltefosine resistance.

bioRxiv · May 19, 2021Microbiology