N. van Rhijn

Distribution and Triazole Susceptibility of Aspergilli from Clinical, Soils and Veterinary Samples in Ogun State, Nigeria.

The paper investigates Aspergillus species distribution and triazole susceptibility in clinical, soil, and veterinary samples from Nigeria, finding high susceptibility to itraconazole and voriconazole across species.

A phylogenetic approach to explore the Aspergillus fumigatus conidial surface-associated proteome and its role in pathogenesis

The paper identifies conidial surface proteins in Aspergillus fumigatus and shows their role in immune evasion during infection.

COVID-19 Associated Pulmonary Aspergillosis isolates are genomically diverse but similar to each other in their responses to infection-relevant stresses

This study analyzes 11 Aspergillus fumigatus isolates from COVID-19 patients with pulmonary aspergillosis, finding genomic diversity but similar stress responses to infection.

Aspergillus fumigatus FhdA transcription factor is important for mitochondrial activity and codon usage regulation during the caspofungin paradoxical effect

This study shows that FhdA regulates mitochondrial activity and tRNA expression in Aspergillus fumigatus during caspofungin tolerance.

Distinct cohorts of Aspergillus fumigatus transcription factors are required for epithelial damage occurring via contact- or soluble effector-mediated mechanisms

This study identifies distinct transcription factor cohorts required for early and late phases of epithelial damage caused by Aspergillus fumigatus.

Exploring a novel genomic safe-haven site in the human pathogenic mould Aspergillus fumigatus.

The paper identifies a conserved genomic safe-haven locus in Aspergillus fumigatus for inserting genetic constructs without affecting phenotype.

Epithelial uptake of Aspergillus fumigatus drives efficient fungal clearance in vivo and is aberrant in Chronic Obstructive Pulmonary Disease (COPD)

The paper shows that airway epithelial cells efficiently kill inhaled Aspergillus fumigatus spores in vivo, but this process is impaired in COPD.

Antagonism of the azoles to olorofim and cross-resistance are governed by linked transcriptional networks in Aspergillus fumigatus

This study identifies antagonism between triazoles and olorofim in Aspergillus fumigatus due to transcriptional regulation of pyrimidine and ergosterol pathways, revealing cross-resistance mechanisms.