Author

G. J. P. L. Kops

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Evolutionary Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Organism:chicken / avian· 1

Frequent Co-Authors

C. Sacristan· 2 shared E. C. Tromer· 2 shared A. Buckle· 1 shared A. G. B. Simpson· 1 shared A. J. Roger· 1 shared A. v. Oudenaarden· 1 shared A. Vertesy· 1 shared B. A. Curtis· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersCell Biology

C. Sacristan

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Author profile →

4 papers

Recent·Most cited

Increased sampling and intra-complex homologies favor vertical over horizontal inheritance of the Dam1 complex

L. E. van Rooijen, E. C. Tromer, J. J. E. van Hooff, G. J. P. L. Kops, B. Snel

The paper analyzes the evolutionary history of the Dam1 complex, finding it originated in the Last Common Ancestor and evolved through stepwise duplications, not horizontal gene transfer.

bioRxiv · Oct 4, 2022Evolutionary Biology

Condensin reorganizes centromeric chromatin during mitotic entry into a bipartite structure stabilized by cohesin

C. Sacristan, K. Samejima, L. Andrade Ruiz, M. L. A. Lambers, A. Buckle, C. A. Brackley, D. Robertson, T. Hori, S. Webb, T. Fukagawa, N. Gilbert, D. Marenduzzo, W. C. Earnshaw, G. J. P. L. Kops

This study shows vertebrate centromeres form a bipartite structure during mitosis, stabilized by condensin and linked by cohesin, which prevents merotelic attachments and chromosomal instability.

bioRxiv · Aug 1, 2022 · PreprintCell Biology

A free-living protist that lacks canonical eukaryotic DNA replication and segregation systems

D. E. Salas-Leiva, E. C. Tromer, B. A. Curtis, J. Jerlstrom-Hultqvist, M. Kolisko, Z. Yi, J. S. Salas-Leiva, L. Gallot-Lavallee, G. J. P. L. Kops, J. M. Archibald, A. G. B. Simpson, A. J. Roger

This study identifies a free-living protist, Carpediemonas membranifera, that lacks canonical eukaryotic DNA replication and segregation systems, suggesting novel mechanisms for these processes.

bioRxiv · Mar 14, 2021Evolutionary Biology

Spindle checkpoint silencing at kinetochores with submaximal microtubule occupancy

B. Etemad, A. Vertesy, T. E. F. Kuijt, C. Sacristan, A. v. Oudenaarden, G. J. P. L. Kops

The paper shows that the SAC responds to intermediate microtubule occupancy by shedding the RZZS-MAD1/2 module but retaining the BUB1/R1 module, allowing SAC silencing at submaximal occupancy while maintaining reactivation potential.

bioRxiv · Nov 16, 2018Cell Biology