G. Jung

The hepatokine FGL1 regulates hepcidin and iron metabolism during the recovery from hemorrhage-induced anemia in mice

Hyperphosphatemia increases inflammation to exacerbate anemia and skeletal muscle wasting independently of FGF23-FGFR4 signaling

This study shows hyperphosphatemia causes inflammation, anemia, and muscle wasting in mice independently of FGF23-FGFR4 signaling, suggesting dietary phosphate restriction may benefit both CKD patients and healthy individuals.

Dual regulation of the actin cytoskeleton by CARMIL-GAP

This paper identifies CARMIL-GAP as a Dictyostelium protein that regulates actin dynamics by GAP activity on Rac1 and capping protein, showing its critical role in phagocytosis and chemotaxis.

Erythroid overproduction of erythroferrone causes iron overload and developmental abnormalities in mice

This study shows that excessive erythroferrone production in mice leads to iron overload and developmental issues by suppressing hepcidin and disrupting BMP signaling.

Hypertrophic cardiomyopathy β-cardiac myosin mutation (P710R) leads to hypercontractility by disrupting super-relaxed state: multiscale measurements and computational modeling

This study investigates the P710R mutation in β-cardiac myosin, showing it causes hypercontractility by disrupting the super-relaxed state, using multiscale experiments and modeling.

Forensic microbial system for high-resolution object provenance

This paper develops a synthetic microbial spore system for high-resolution object provenance tracking with rapid decoding and biocontainment.

Characterization of fluorescent proteins with intramolecular photostabilization

This study screens covalently-linked photostabilizers on fluorescent proteins, finding that azobenzene derivatives significantly enhance photostability compared to other stabilizers.