Author

G. Kildisiute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Assay:scRNA-seq· 2 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1

Frequent Co-Authors

A. Piapi· 3 shared C. Thevanesan· 3 shared M. D. Young· 3 shared M. Haniffa· 3 shared C. Burke· 2 shared D. Rampling· 2 shared E. Khabirova· 2 shared E. Prigmore· 2 shared

Activity by Year

2016-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

A. Piapi

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Transcriptional signals of dedifferentiation in human cancer

G. Kildisiute, M. Kalyva, R. Elmentaite, S. van Dongen, C. Thevanesan, A. Piapi, K. Ambridge, E. Prigmore, M. Haniffa, S. A. Teichmann, K. Straathof, I. Cortes-Ciriano, S. Behjati, M. D. Young

This study examines dedifferentiation in cancer using single-cell atlases, finding that adult cancers do not revert to an embryonic state but retain foetal signals, while childhood cancers show universal foetal state features.

bioRxiv · Nov 28, 2022 · PreprintCancer Biology

Tumor to normal single cell mRNA comparisons reveal a pan-neuroblastoma cancer cell

G. Kildisiute, W. M. Kholosy, M. D. Young, K. Roberts, R. Elmentaite, S. R. van Hooff, E. Khabirova, A. Piapi, C. Thevanesan, E. Bugallo Blanco, C. Burke, L. Mamanova, P. Lijnzaad, T. Margaritis, F. C. P. Holstege, , S. Behjati

The paper compares tumor and normal single-cell mRNA data to show neuroblastoma cells resemble fetal sympathoblasts across diverse samples.

bioRxiv · Jun 22, 2020Cancer Biology

Cellular mRNA signals in human kidney tumors

M. D. Young, T. J. Mitchell, L. M. Custers, T. Margaritis, F. Morales, K. Kwakwa, E. Khabirova, G. Kildisiute, T. R. Oliver, R. R. d. Krijger, M. M. v. d. Heuvel-Eibrink, F. Comitani, A. Piapi, E. B. Blanco, C. Thevanesan, , Holste

This study analyzes mRNA signals in 1,300 kidney tumors to determine their differentiation state and origin, finding that childhood tumors show fetal signals while most adult tumors do not, with exceptions in certain cancer types.

bioRxiv · Mar 19, 2020Cancer Biology

Analyses of the core eukaryotic protein subunit of telomerase support extensive adaptation to different evolutionary and life histories in the Metazoa

A. G. Lai, N. Pouchkina-Stantcheva, A. Di Donfrancesco, G. Kildisiute, S. Sahu, A. Aboobaker

This study analyzes TERT sequence and regulatory evolution across Metazoa, revealing extensive adaptation to diverse life histories and evolutionary pressures.

bioRxiv · Dec 2, 2016Evolutionary Biology