Author

G. L. Szeto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Assay:scRNA-seq· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. T. Heubeck· 2 shared C. R. Roll· 2 shared J. Reading· 2 shared L. A. Becker· 2 shared L. T. Graybuck· 2 shared L. Y. Okada· 2 shared M.-P. L. Pebworth· 2 shared P. C. Genge· 2 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

A. T. Heubeck

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Distinct Heterogeneity in the Naive T cell Compartments of Children and Adults

C. E. Gustafson, Z. Thomson, Z. He, E. Swanson, K. Henderson, M.-P. L. Pebworth, L. Y. Okada, A. T. Heubeck, C. R. Roll, V. Hernandez, M. D. Weiss, P. C. Genge, J. Reading, J. R. Giles, S. Manne, , P. J. Skene

The study identifies age-related differences in naive T cell compartments between children and adults, showing distinct molecular reprogramming in CD4 and CD8 subsets.

bioRxiv · Oct 4, 2022 · PreprintImmunology

Lipid-polymer hybrid nanoparticles utilize B cells and dendritic cells to elicit distinct antigen-specific CD4+ and CD8+ T cell responses

M. H. Zhang, B. L. Scotland, Y. Jiao, E. M. Slaby, N. Truong, G. Stephanie, R. M. Pearson, G. L. Szeto

This study develops lipid-polymer hybrid nanoparticles to deliver antigens to APCs, showing they elicit distinct CD4+ and CD8+ T cell responses via different uptake mechanisms.

bioRxiv · Jan 23, 2022Bioengineering

Targeted Delivery of Chloroquine to Plasmacytoid Dendritic Cells Enhances Inhibition of the Type I Interferon Response

M. E. Allen, A. Golding, V. Rus, N. B. Karabin, S. Li, C. Lescott, S. Bobbala, E. A. Scott, G. L. Szeto

This study shows that delivering chloroquine via nanocarriers specifically to plasmacytoid dendritic cells reduces type I interferon production in SLE models.

ACS Biomaterials Science & Engineering · Nov 23, 2021Peer-reviewedBioengineering

Longitudinal immune dynamics of mild COVID-19 define signatures of recovery and persistence

A. Talla, S. V. Vasaikar, M. P. Lemos, Z. Moodie, M.-P. L. Pebworth, K. E. Henderson, K. W. Cohen, J. L. Czartoski, L. Lai, M. S. Suthar, A. T. Heubeck, P. C. Genge, C. R. Roll, M. Weiss, J. Reading, , T. F. Bumol

The paper profiles longitudinal immune responses in mild COVID-19 patients to identify recovery and persistence signatures.

bioRxiv · May 26, 2021 · PreprintImmunology

Yap suppresses T cell function and infiltration in the tumor microenvironment

E. Stampouloglou, A. Federico, E. Slaby, S. Monti, G. L. Szeto, X. Varelas

This study shows that Yap inhibits T cell function and infiltration in tumors, and its inhibition enhances anti-tumor immunity.

bioRxiv · Jun 5, 2019Cancer Biology