Author

G. Tseng

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Immunology· 2

Signature Assays, Organisms & Methods

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Organism:human· 5 Assay:bulk RNA-seq· 4 Research Focus:cell type annotation· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

S. Oesterreich· 4 shared A. V. LEE· 3 shared C. T. Wallace· 2 shared J. Carroll· 2 shared L. Zhu· 2 shared M. E. Yates· 2 shared P. C. Lucas· 2 shared S. C. Watkins· 2 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersCancer Biology

S. Oesterreich

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Author profile →

5 papers

Recent·Most cited

The chemotherapy-induced senescence-associated secretome promotes cell detachment and metastatic dissemination through metabolic reprogramming

A. R. Cole, R. Buj, A. Uboveja, E. Levasseur, H. Wang, K. M. Kedziora, A. Chatoff, A. Andress Huacachino, M. M. Marcinkiewicz, A. Amalric, B. Yang, N. K. Tangudu, J. Danielson, A. Taher Elhaw, S. White, , K. M. Aird

This study shows that chemotherapy-induced senescence-associated secretome promotes metastasis in ovarian cancer by reprogramming metabolism and increasing cell detachment.

bioRxiv · Dec 2, 2023Cancer Biology

EstroGene database reveals diverse temporal, context-dependent and directional estrogen receptor regulomes in breast cancer

Z. Li, T. Li, M. E. Yates, Y. Wu, A. Ferber, L. Chen, D. D. Brown, J. Carroll, M. J. Sikora, G. Tseng, S. Oesterreich, A. V. LEE

The paper establishes the EstroGene database, which compiles 246 experiments from 136 datasets to analyze estrogen receptor regulomes in breast cancer, revealing diverse temporal, context-dependent, and directional responses.

bioRxiv · Jan 30, 2023 · PreprintCancer Biology

Human placental villi immune cells help maintain homeostasis in utero

L. Konnikova, J. M. Toothaker, O. Olaloye, B. T. McCourt, C. C. McCourt, R. M. Case, P. Liu, D. Yimlamai, G. Tseng

The paper identifies immunosuppressive signatures and functional maturity of fetal immune cells in human placental villi across gestational ages.

bioRxiv · Jul 14, 2021 · PreprintImmunology

Hotspot ESR1 mutations are multimodal and contextual drivers of breast cancer metastasis

Z. Li, Y. Wu, M. E. Yates, N. Tasdemir, A. Bahreini, J. Chen, K. M. Levine, N. M. Priedigkeit, S. Ali, L. Buluwela, S. Arnesen, J. Gertz, J. K. Richer, B. Troness, D. El-Ashry, , S. Oesterreich

This study identifies ESR1 mutations as drivers of breast cancer metastasis by altering cell adhesion and migration through genomic and transcriptomic reprogramming.

bioRxiv · Feb 10, 2021 · PreprintCancer Biology

Metastatic breast cancers have reduced immune cell recruitment but harbor increased macrophages relative to their matched primary tumors

L. Zhu, J. L. Narloch, S. Onkar, M. Joy, C. Luedke, A. Hall, R. Kim, K. Pogue-Geile, S. Sammons, N. Nayyar, U. Chukwueke, P. K. Brastianos, C. K. Anders, A. C. Soloff, D. A. Vignali, , A. V. Lee

The paper compares immune cell infiltration in primary and metastatic breast tumors, finding reduced immune cell abundance but increased M2-like macrophages in metastases.

bioRxiv · Jan 20, 2019Immunology