A human adenovirus encoding IFN-γ can transduce Tasmanian devil facial tumour cells and upregulate MHC-I
A. N. Kayigwe, J. M. Darby, A. B. Lyons, A. L. Patchett, L. Lisowski, G.-S. Liu, A. S. Flies
This study shows a human adenovirus encoding IFN-γ can upregulate MHC-I in Tasmanian devil tumor cells, suggesting its potential as a vaccine platform.
bioRxiv · May 29, 2022Immunology