Martin H. Berryer

This study uses adeno-associated virus to image and analyze 3D morphology and connectivity of neurons and astrocytes in living human midbrain organoids over time.

This study integrates iPSC-derived microglia into human midbrain organoids to enhance microglial maturation and inflammatory signaling, revealing altered transcriptional signatures in dopaminergic neurons and astrocytes.

This study shows that p75NTR upregulation after perinatal hypoxia impairs PV GABAergic cell maturation and leads to cognitive deficits in adult mice, which can be reversed by p75NTR inhibition.

This study develops a rapid, scalable method to generate functional human astrocytes from pluripotent stem cells using NGN2 induction, showing high homogeneity and disease relevance.

The paper develops an automated high-content synaptic phenotyping platform in human neurons and astrocytes, identifying BET inhibitors as key regulators of synapse assembly.