Author

Guangyi Liang

Chinese Academy of Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Approach:genetic perturbation / CRISPR· 2 Research Focus:host-pathogen & immune response· 2 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Ming LiiD· 2 shared Rafael Pinilla‐RedondoiD· 2 shared Rui Wang· 2 shared Cai Lei· 1 shared Chao LiuiD· 1 shared Chao LiuiD· 1 shared Eugene V. KooniniD· 1 shared Feiyue ChengiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersMicrobiology

Ming LiORCID

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2 papers

Recent·Most cited

Pseudomonas aeruginosa CRISPR-Cas primes a minimal proline-codon toxin to abort anti-CRISPR phages

Rui Wang, Chao Liu, Ping Li, J Q Xu, Guangyi Liang, Yali Wu, Xinyu Jiang, Rui Zhao, Rafael Pinilla‐Redondo, Shuai Le, Guangxin Luan, Ming Li

The paper shows Pseudomonas aeruginosa uses a CRISPR-Cas system to silence a proline-codon toxin that stops phage growth, revealing a defense mechanism against anti-CRISPR phages.

bioRxiv · Jun 3, 2026 · PreprintMicrobiology

Phage CRISPR-like regulatory RNAs silence multilayered bacterial immune systems

Chao Liu, Zhihua Li, Rui Wang, Wenhe Wang, Jiachen Yao, Junyuan Xue, Xiaoyu Du, Jing Xu, Guangyi Liang, Feiyue Cheng, Xiaoyu Du, Linlin Guan, Mario Rodríguez Mestre, Jun Du, Cai Lei, , Ming Li

The paper identifies viral crlRNAs that suppress bacterial immunity by reprogramming Cas proteins and demonstrates their potential for mammalian genome editing.

bioRxiv · Oct 29, 2024 · PreprintMicrobiology