Author

Zhihua Li

Chinese Academy of Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Anuk Das· 1 shared Ari Grinspan· 1 shared Arthur MorthaiD· 1 shared Bruce E. SandsiD· 1 shared Cai Lei· 1 shared Chao LiuiD· 1 shared Dermot P.B. McGoverniD· 1 shared Dirk GeversiD· 1 shared

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2018-2024 · peak 1/yr

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10 top collaborators · 24 mutual co-author links

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1 shared paperImmunology

Anuk Das

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2 papers

Recent·Most cited

Phage CRISPR-like regulatory RNAs silence multilayered bacterial immune systems

Chao Liu, Zhihua Li, Rui Wang, Wenhe Wang, Jiachen Yao, Junyuan Xue, Xiaoyu Du, Jing Xu, Guangyi Liang, Feiyue Cheng, Xiaoyu Du, Linlin Guan, Mario Rodríguez Mestre, Jun Du, Cai Lei, , Ming Li

The paper identifies viral crlRNAs that suppress bacterial immunity by reprogramming Cas proteins and demonstrates their potential for mammalian genome editing.

bioRxiv · Oct 29, 2024 · PreprintMicrobiology

Inflammatory bowel disease microbiotas alter gut CD4 T-cell homeostasis and drive colitis in mice

Graham J. Britton, Eduardo J. Contijoch, Ilaria Mogno, Olivia H. Vennaro, Sean R. Llewellyn, Ruby Ng, Zhihua Li, Arthur Mortha, Miriam Merad, Anuk Das, Dirk Gevers, Dermot P.B. McGovern, Namita Singh, Jonathan Braun, Jonathan P. Jacobs, , Jeremiah J. Faith

The paper shows that IBD microbiotas alter gut CD4 T-cell balance and drive colitis in mice, with specific T-cell profiles predicting disease status and severity.

bioRxiv · Mar 6, 2018 · PreprintImmunology