Author

H. W. Nijman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

M. de Bruyn· 3 shared F. Foijer· 2 shared A. Damaskou· 1 shared A. de Bruin· 1 shared A. E. Tijhuis· 1 shared A. Eerkens· 1 shared A. Kol· 1 shared A. Plat· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersImmunology

M. de Bruyn

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cancer tolerance to chromosomal instability is driven by Stat1 inactivation in vivo

M. Schubert, C. Hong, L. J. Jilderda, M. Requesens-Rueda, A. E. Tijhuis, J. E. Simon, P. L. Bakker, J. Cooper, A. Damaskou, R. Wardenaar, B. Bakker, S. Gupta, A. van den Brink, L. Andrade-Ruiz, M. H. Koster, , F. Foijer

The paper identifies Stat1 inactivation as a mechanism by which aneuploid cancers evade immune surveillance in mice and humans.

bioRxiv · Dec 3, 2021 · PreprintCancer Biology

Rapid and efficient generation of antigen-specific isogenic T cells from cryopreserved blood samples

A. Eerkens, A. Vledder, N. van Rooij, F. Foijer, H. W. Nijman, M. de Bruyn

This study demonstrates an efficient CRISPR/Cas9 protocol for modifying ex vivo human T cells without affecting viability or antigen-specific responses.

bioRxiv · Nov 12, 2021Immunology

TGF-β induced CXCL13 in CD8+ T cells is associated with tertiary lymphoid structures in cancer

H. H. Workel, J. M. Lubbers, R. Arnold, T. M. Prins, P. van der Vlies, K. de Lange, T. Bosse, I. C. van Gool, F. A. Eggink, M. C. Wouters, F. L. Komdeur, C. L. Creutzberg, A. Kol, A. Plat, M. Glaire, , M. de Bruyn

This study identifies CD8+ T cells as a new source of CXCL13, which contributes to tertiary lymphoid structure formation in tumors through TGF-β signaling.

bioRxiv · Apr 18, 2018Immunology