Primitive Hepatoblasts Driving Early Liver Development
Kentaro Iwasawa, Hiroyuki Koike, Hasan Al Reza, Yuka Milton, Keishi Kishimoto, Konrad Thorner, Marissa Granitto, Norikazu Saiki, Connie Santangelo, Kathryn Glaser, Masaki Kimura, Alexander J. Bondoc, Hee-Wong Lim, Mitsuru Morimoto, Makiko Iwafuchi, , Takanori Takebe
The paper identifies and characterizes a new population of early hepatoblasts in mouse and human liver development, showing their role in liver bud formation and their decline in later stages.
bioRxiv · Jun 8, 2025 · PreprintDevelopmental Biology