Author

Connie Santangelo

Cincinnati Children's Hospital Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Assay:scRNA-seq· 2 Approach:experimental assay· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Alexander J. BondociD· 2 shared Hasan Al RezaiD· 2 shared Kathryn GlaseriD· 2 shared Kentaro IwasawaiD· 2 shared Takanori TakebeiD· 2 shared Aaron M. ZorniD· 1 shared Abid Al Reza· 1 shared Hee-Wong Lim· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersDevelopmental Biology

Alexander J. BondocORCID

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2 papers

Recent·Most cited

Primitive Hepatoblasts Driving Early Liver Development

Kentaro Iwasawa, Hiroyuki Koike, Hasan Al Reza, Yuka Milton, Keishi Kishimoto, Konrad Thorner, Marissa Granitto, Norikazu Saiki, Connie Santangelo, Kathryn Glaser, Masaki Kimura, Alexander J. Bondoc, Hee-Wong Lim, Mitsuru Morimoto, Makiko Iwafuchi, , Takanori Takebe

The paper identifies and characterizes a new population of early hepatoblasts in mouse and human liver development, showing their role in liver bud formation and their decline in later stages.

bioRxiv · Jun 8, 2025 · PreprintDevelopmental Biology

Self-Assembled Generation of Multi-zonal Liver Organoids from Human Pluripotent Stem Cells

Hasan Al Reza, Connie Santangelo, Kentaro Iwasawa, Abid Al Reza, Sachiko Sekiya, Kathryn Glaser, Alexander J. Bondoc, Jonathan Merola, Takanori Takebe

This study develops self-assembled multi-zonal liver organoids from human pluripotent stem cells, revealing zonal-specific functions and epigenetic mechanisms that mimic human liver architecture.

Nature · Apr 16, 2025Peer-reviewedBioengineering