Author

Henry Gerdes

Queen Mary University of London

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:metabolomics· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Audrey LumeauiD· 1 shared Daniel Egbase· 1 shared David HopkinsiD· 1 shared Ella-Louise HubberiD· 1 shared Emilie L. AlardiD· 1 shared Faraz K. MardakhehiD· 1 shared FB CopleyiD· 1 shared Gavin A. BewickiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

Audrey LumeauORCID

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2 papers

Recent·Most cited

High levels of DNA replication initiation factors indicate ATR inhibitor sensitivity via excessive origin firing

Audrey Lumeau, Pauline Luise Pfuderer, S De Angelis, James A. Scarth, Molly A Guscott, Nadeem Shaikh, FB Copley, Henry Gerdes, Emilie L. Alard, Pedro R. Cutillas, Faraz K. Mardakheh, Michael A. Boemo, Josep V. Forment, Sarah Elizabeth McClelland

This study identifies that high levels of DNA replication initiation factors correlate with ATR inhibitor sensitivity due to excessive origin firing in cancer cells.

bioRxiv · Feb 27, 2025 · PreprintCancer Biology

NAMPT activity plays a key role in driving autoimmune processes that characterize type 1 diabetes development in mice

Daniel Egbase, Sophie R. Sayers, Naila Haq, Jithu James Varghese, Vesela Gesheva, Sreya Bhattacharya, Jay Kynaston, Ella-Louise Hubber, Lorna I. F. Smith, Timothy J. Pullen, Henry Gerdes, Vivian K. Lee, David Hopkins, Min Zhao, Yee Cheah, , Paul Caton

This study shows that inhibiting NAMPT reduces inflammation and beta-cell damage in T1D by blocking cytokine-mediated immune responses in mice.

bioRxiv · Jan 14, 2025 · PreprintCell Biology