Author

Cyril Djari

University of GenevaORCID 0000-0001-7666-9024Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1

Frequent Co-Authors

Aitana Perea-GómeziD· 2 shared Chloé MayèreiD· 2 shared Dagmar WilhelmiD· 2 shared Françoise KühneiD· 2 shared Marie‐Christine ChaboissieriD· 2 shared Serge NefiD· 2 shared Agathe RozieriD· 1 shared Andy GreenfieldiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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2 shared papersDevelopmental Biology

Aitana Perea-GómezORCID

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3 papers

Recent·Most cited

PKA disrupts adult ovarian identity circuits through direct inhibition of TRIM28-chromatin binding

Florian Chaleil, Lionel Le Gallic, Isabelle Sahut‐Barnola, Joris Mordier, Stéphanie Le Gras, Sylvain Roumeau, Céline Keime, Cyril Djari, Antoine Vigier, L. Badoil, Pierre Val, Jean‐Christophe Pointud, Constantine A. Stratakis, Florence M. Cammas, Antoine Martinez, , Anne‐Marie Lefrançois‐Martinez

This study shows PKA inhibits TRIM28-chromatin binding in ovarian granulosa cells, disrupting ovarian identity through SUMOylation dysregulation.

bioRxiv · Oct 7, 2026 · PreprintPhysiology

Ovarian development is driven by early spatiotemporal priming of the coelomic epithelium

Cyril Djari, Chloé Mayère, Maëva Guy, Aitana Perea-Gómez, Laura Bellutti, Paul Barreau, Herta Ademi, Agathe Rozier, Anthony S. Martinez, Tyler J. Gibson, Françoise Kühne, Cassandre Guérin, Dagmar Wilhelm, Gabriel Livera, Jennifer McKey, , Serge Nef

This study shows that ovarian cellular diversity arises from spatially organized, transcriptionally heterogeneous coelomic epithelium progenitors in fetal mouse and human ovaries, which are primed toward supporting or steroidogenic identities.

bioRxiv · Sep 24, 2025 · PreprintDevelopmental Biology

Origin, specification and differentiation of a rare supporting-like lineage in the developing mouse gonad

Chloé Mayère, Violaine Regard, Aitana Perea-Gómez, Corey Bunce, Yasmine Neirijnck, Cyril Djari, Natividad Bellido-Carreras, Pauline Sararols, Richard Reeves, Simon Greenaway, Michelle Simon, Pam Siggers, Diana Condrea, Françoise Kühne, Ivana Gantar, , Serge Nef

The paper identifies and characterizes a previously uncharacterized supporting-like cell lineage in developing mouse gonads, showing its origin, specification, and sex-specific differentiation.

Science Advances · May 25, 2022Peer-reviewedDevelopmental Biology